SynthesisWorld journal of gastroenterology2015
Impact of lymph node micrometastasis on gastric carcinoma prognosis: a meta-analysis.
Synthesis in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Deep learning-based prediction of lymph node metastasis and occult tumor cells in gastric cancer using histopathological images: a retrospective study.British journal of cancer · 2026Article
- Prognostic Value of Lymph-Node Micrometastases and Isolated Tumour Cells in Gastric Cancer.Cureus · 2026Article
- Clinical Application of Indocyanine Green Fluorescence Technology in Laparoscopic Radical Gastrectomy.Frontiers in oncology · 2022Article
- Article
- Impact of Lymph Nodes Examined on Survival in ypN0 Gastric Cancer Patients: a Population-Based Study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Letter to the editor: reply to Antonio Ieni "Intratumoral HER2 heterogeneity in early gastric carcinomas: potential bias in therapeutical management".Virchows Archiv : an international journal of pathology · 2019Article
- Aberrant Cytokeratin 20 mRNA Expression in Peripheral Blood and Lymph Nodes Indicates Micrometastasis and Poor Prognosis in Patients With Gastric Carcinoma.Technology in cancer research & treatment · 2019Article
- Rottlerin promotes autophagy and apoptosis in gastric cancer cell lines.Molecular medicine reports · 2018Article
- CREB promotes laryngeal cancer cell migration via MYCT1/NAT10 axis.OncoTargets and therapy · 2018Article
- Prognostic value of fibrosis ratio in metastatic lymph nodes of node-positive advanced gastric cancer.Medicine · 2018Article
- Prognostic Significance of Solitary Lymphnode Metastasis and Micrometastasis in Gastric Cancer.Frontiers in surgery · 2018Review
- MiR-381 inhibits migration and invasion in human gastric carcinoma through downregulatedting SOX4.Oncology letters · 2017Article
- Clinical significance of lymph nodes micrometastasis in conventionally node-negative advanced gastric cancer.Updates in surgery · 2017Article
- Current status of lymph node micrometastasis in gastric cancer.Oncotarget · 2017Review
- The prognostic value of negative lymph node count for patients with gastric cancer who received preoperative radiotherapy.Oncotarget · 2017Article
- Negative lymph node count is an independent prognostic factor for patients with rectal cancer who received preoperative radiotherapy.BMC cancer · 2017Article
- Recurrence of a pT2N0cM0 Lower Third Gastric Cancer with No. 6 Lymph Node Micrometastasis after R0 Extended Surgery. Should Adjuvant Therapy be Performed in Conventionally Node-Negative but Micrometastasis-Positive pT2 Gastric Cancer?Journal of gastrointestinal cancer · 2017Article
- Prognostic impact of nodal status and therapeutic implications.Translational gastroenterology and hepatology · 2017Review
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the prognostic significance of lymph node micrometastasis (LNMM) in patients with gastric carcinoma.
methodsTwo reviewers independently searched electronic databases including PubMed, EMBASE, the Cochrane Database of Systematic Reviews, the Cochrane Controlled Studies Register, and the China National Knowledge Infrastructure electronic database between January 1996 and January 2014. Strict literature retrieval and data extraction were performed to extract relevant data. Data analysis was conducted using RevMan 5.2.4 software, and relative risks (RRs) for patient death in five years and recurrence were calculated. A fixed- or random-effects model was selected to pool and a forest plot was used to display RRs.
resultsTwelve cohort studies containing a total of 1684 patients were identified. LNMM positivity was worse than LNMM negativity with regards to the number of patients who died in five years. The effects of LNMM positivity in patients with gastric cancer of different T-stages remain unclear. LNMM in patients with gastric carcinoma was also associated with a higher recurrence rate. With regards to the number of patients who died in five years, Asian patients were worse than European and Australian patients.
conclusionWe recommend that LNMM should not be used as a gold standard for prognosis evaluation in patients with gastric cancer in clinical settings until more high quality trials are available.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.