Evidence map›Paper›PMID 25663728›Full record

ArticleInternational journal of behavioral development2015

A neurogenetics approach to defining differential susceptibility to institutional care.

Zoe H Brett, Margaret Sheridan, Kate Humphreys, Anna Smyke, Mary Margaret Gleason, Nathan Fox, Charles Zeanah, Charles Nelson, Stacy Drury

Open access · greenAbstract read
In one paragraph

Article in International journal of behavioral development, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Adolescent neurobiological susceptibility to social context.Developmental cognitive neuroscience · 2016
    Review
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Zoe H BrettTulane University, USA.
Margaret SheridanBoston Children's Hospital and Harvard Medical School, USA.
Kate HumphreysTulane University, USA.
Anna SmykeTulane University School of Medicine, USA.
Mary Margaret GleasonTulane University, USA.
Nathan FoxUniversity of Maryland, USA.
Charles ZeanahTulane University, USA.
Charles NelsonBoston Children's Hospital and Harvard Medical School, USA.
Stacy DruryTulane Medical Center, USA.
Tulane University · USBoston Children's Hospital · USTulane Medical Center · USUniversity of Maryland, College Park · US

Funding

The Relation Between Early Psychosocial Deprivation and Mental Health at 12 YearsR01MH091363 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI FOX, NATHAN A, NELSON, CHARLES ALEXANDER · 2010 to 2024
$9.2M
Telomeres as an Epigenetic Marker of Neurodevelopment and Early AdversityR21MH094688 · NIMH · TULANE UNIVERSITY OF LOUISIANA · PI DRURY, STACY SCHMIDT · 2011 to 2012
$414k
NIMH NIH HHS R01 MH091363NIMH NIH HHS R21 MH094688
6 · The paper itself

Abstract

An individual's neurodevelopmental and cognitive sequelae to negative early experiences may, in part, be explained by genetic susceptibility. We examined whether extreme differences in the early caregiving environment, defined as exposure to severe psychosocial deprivation associated with institutional care compared to normative rearing, interacted with a biologically informed genoset comprising

Indexed as

cognitive functiongene x environmentgenosetneurodevelopment

Identifiers

PMID25663728
PMCPMC4317330
OpenAlexW2113094863

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.