ArticleJournal of the National Cancer Institute2015
Comparative effectiveness of laparoscopy vs open colectomy among nonmetastatic colon cancer patients: an analysis using the National Cancer Data Base.
Article in Journal of the National Cancer Institute, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Pooled it
- Robotic ambulatory colorectal resections: a systematic review.Journal of robotic surgery · 2024Pooled it
- Accelerated enhancedBMJ open · 2017Trial
- Temporal trends in outpatient right colectomy: a contemporary multistate study.Surgical endoscopy · 2025Article
- Laparoscopic Radical Colectomy with Complete Mesocolic Excision Offers Similar Results Compared with Open Surgery.Medicina (Kaunas, Lithuania) · 2025Article
- Rise in Minimally Invasive Surgery for Colorectal Cancer Is Associated With Adoption of Robotic Surgery.Diseases of the colon and rectum · 2025Article
- Does the pre-conversion platform matter? A comparison of laparoscopic and robotic converted to open colectomies.Surgical endoscopy · 2024Article
- Perioperative and oncological outcomes following robotic en bloc multivisceral resection for colorectal cancer.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024Article
- Possible Advantages of Minimal-Invasive Approaches in Rectal Cancer Surgery: A Nationwide Analysis.Journal of clinical medicine · 2023Article
- Short term results in a population based study indicate advantage for laparoscopic colon cancer surgery versus open.Scientific reports · 2023Article
- Association of hospital factors and socioeconomic status with the utilization of minimally invasive surgery for colorectal cancer over a decade.Surgical endoscopy · 2022Article
- Quality and Location of the Surgical Episode Mediate a Large Proportion of Socioeconomic-Based Survival Disparities in Patients with Resected Stage I-III Colon Cancer.Annals of surgical oncology · 2022Article
- [Evidence in minimally invasive oncological surgery of the colon and rectum].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Review
- Impact of minimally invasive gastrectomy on use of and time to adjuvant chemotherapy for gastric adenocarcinoma.Journal of surgical oncology · 2020Article
- Essential advances in surgical and adjuvant therapies for colorectal cancer 2018-2019.Annals of gastroenterological surgery · 2020Review
- Morbidity and Mortality After Surgery for Nonmalignant Colorectal Polyps: A 10-Year Nationwide Analysis.The American journal of gastroenterology · 2019Article
- Laparoscopic approach for left-sided T4 colon cancer is a safe and feasible procedure, compared to open surgery.Surgical endoscopy · 2019Article
- Long-term oncologic outcomes after laparoscopic vs. open colon cancer resection: a high-quality population-based analysis in a Southern German district.Surgical endoscopy · 2018Observational
- Laparoscopy may decrease morbidity and length of stay after elective colon cancer resection, especially in frail patients: results from an observational real-life study.Surgical endoscopy · 2017Observational
- Patient, Hospital, and Geographic Disparities in Laparoscopic Surgery Use Among Surveillance, Epidemiology, and End Results-Medicare Patients With Colon Cancer.Diseases of the colon and rectum · 2017Observational
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundRandomized clinical trials showed that laparoscopic colectomy (LC) is superior to open colectomy (OC) in short-term surgical outcomes; however, the generalizability among real-world patients is not clear.
methodsThe National Cancer Data Base was used to identify stage I-III colon cancer patients age 18 to 84 years in 2010 and 2011. A propensity score analysis with 1:1 matching (PS) was used to avoid the effect of treatment selection bias. Patients were clustered at the hospital level for multilevel regression analyses. The main outcomes measured were 30-day mortality, unplanned readmissions, length of stay (LOS), and initiation of adjuvant chemotherapy among stage III patients. All statistical tests were two-sided.
resultsA total of 45 876 patients were analyzed, 18 717 (41%) LC and 27 159 (59%) OC. After PS matching, there were 18 230 patients in both groups and they were well balanced on their covariables. Compared with OC, LC showed consistent benefits in 30-day mortality (1.3% vs 2.3 %, odds ratio [OR] = 0.59, 95% confidence interval [CI] = 0.49 to 0.69, P < .001) and LOS (median 5 vs 6 days, incident rate ratio = 0.83, 95% CI = 0.8 to 0.84, P < .001). LC was also associated with a higher rate of adjuvant chemotherapy use in stage III patients (72.3% vs 67.0%, P < .001). LC was more likely to be performed by high-volume surgeons in high-volume hospitals, but there was no significant effect of the hospital/surgeon volume on short-term outcomes.
conclusionIn routine clinical practice, laparoscopic colectomy is associated with lower 30-day mortality, shorter length of stay, and greater likelihood of adjuvant chemotherapy initiation among stage III colon cancer patients when compared with open colectomy.
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