ArticleInternational urology and nephrology2015
Intradetrusor injection of adult muscle-derived cells for the treatment of underactive bladder: pilot study.
Article in International urology and nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Autologous adipose-derived mesenchymal stem cell therapy reverses detrusor underactivity: open clinical trial.Stem cell research & therapy · 2023Trial
- Longitudinal Pilot Study of Progressive Urethral Sub-Obstruction in a Canine Model: Bladder Functional and Structural Changes and Exploratory Evaluation of Autologous Mesenchymal Stem Cells.Veterinary sciences · 2026Article
- Low-Intensity Extracorporeal Shock Wave Therapy Ameliorates Detrusor Hyperactivity with Impaired Contractility via Transient Potential Vanilloid Channels: A Rat Model for Ovarian Hormone Deficiency.International journal of molecular sciences · 2024Article
- Underactive Bladder and Detrusor Underactivity: New Advances and Prospectives.International journal of molecular sciences · 2023Review
- Tissue Engineering and Stem Cell Therapy in Neurogenic Bladder Dysfunction: Current and Future Perspectives.Medicina (Kaunas, Lithuania) · 2023Review
- Detrusor Underactivity in Men with Bladder Outlet Obstruction.Biomedicines · 2022Review
- Magnetic soft robotic bladder for assisted urination.Science advances · 2022Article
- Human amniotic fluid stem cells can alleviate detrusor dysfunction caused by bladder outlet obstruction in rats.Scientific reports · 2022Article
- Telmisartan inhibits bladder smooth muscle fibrosis in neurogenic bladder rats.Experimental and therapeutic medicine · 2022Article
- Irreversible Bladder Remodeling Induced by Fibrosis.International neurourology journal · 2021Article
- Contemporary application of autologous muscle-derived cells for urinary sphincter regeneration.World journal of urology · 2020Review
- Therapeutic effect of adipose-derived regenerative cells on bladder function in rats with underactive bladder.Nagoya journal of medical science · 2020Article
- Management of Urinary Incontinence With Underactive Bladder: A Review.International neurourology journal · 2020Article
- Current and Future Directions of Stem Cell Therapy for Bladder Dysfunction.Stem cell reviews and reports · 2020Review
- Stem cell in urology-are we at the cusp of a new era?Translational andrology and urology · 2018Review
- Recent advances in the understanding and management of underactive bladder.F1000Research · 2018Review
- New therapeutic directions to treat underactive bladder.Investigative and clinical urology · 2017Review
- Addressing challenges in underactive bladder: recommendations and insights from the Congress on Underactive Bladder (CURE-UAB).International urology and nephrology · 2017Review
- Underactive Bladder.Current urology reports · 2016Review
- Neurogenic Causes of Detrusor Underactivity.Current bladder dysfunction reports · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We conducted the first-regenerative medicine cellular therapy for underactive bladder (UAB) in an FDA-approved, compassionate-use IND trial to evaluate treatment safety and potential clinical efficacy of autologous muscle-derived stem cells (AMDC) on a patient with UAB. No study-related adverse events or side effects were reported. In the 1-year follow-up period, the subject denied any gross hematuria, urgency, frequency or infection. A reduction in maximum cystometric capacity from 844 to 663 mL was observed, and the patient was able to void small amounts but continues to require self-catheterization 1 year after AMDC injection. Intradetrusor injection of AMDC is safe, minimally invasive and a promising treatment option for the UAB.
Indexed as
Identifiers
25663053What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.