Evidence map›Paper›PMID 25662297›Full record

ArticleThe American journal on addictions2015

Incarceration and health outcomes in HIV-infected patients: the impact of substance use, primary care engagement, and antiretroviral adherence.

Emily A Wang, Kathleen A McGinnis, Jessica B Long, Kathleen M Akgün, E Jennifer Edelman, David Rimland, Karen H Wang, Amy C Justice, David A Fiellin

Open access · greenAbstract read
In one paragraph

Article in The American journal on addictions, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  7. Frequency and Duration of Incarceration and Mortality Among US Veterans With and Without HIV.Journal of acquired immune deficiency syndromes (1999) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Emily A WangYale University School of Medicine, New Haven, Connecticut.
Kathleen A McGinnisVA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania.
Jessica B LongYale University School of Medicine, New Haven, Connecticut.
Kathleen M AkgünYale University School of Medicine, New Haven, Connecticut.
E Jennifer EdelmanYale University School of Medicine, New Haven, Connecticut.
David RimlandAtlanta VA Medical Center and Emory University School of Medicine, Atlanta, Georgia.
Karen H WangYale University School of Medicine, New Haven, Connecticut.
Amy C JusticeYale University School of Medicine, New Haven, Connecticut.
David A FiellinYale University School of Medicine, New Haven, Connecticut.
Yale University · USEmory University · USVA Pittsburgh Healthcare System · US

Funding

YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAMUL1RR024139 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$56.8M
Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Alcohol Associated Outcomes Among HIV+/- Aging VeteransU10AA013566 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2006 to 2010
$12.7M
Alcohol Associated Outcomes Among HIV+/-Aging VeteransU01AA013566 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2002 to 2005
$10.1M
Alcohol and Multisubstance Use in the Veterans Aging Cohort StudyU01AA020790 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$7.7M
Sex Disparities in Overall Response to ART Among HIV Infected IndividualsU24AA020794 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$5.5M
Improving Cardiovascular Outcomes in Individuals with a History of IncarcerationK23HL103720 · NHLBI · YALE UNIVERSITY · PI WANG, EMILY AI-HUA · 2010 to 2014
$692k
MEDIATORS OF AGE ASSOCIATED OUTCOMES IN HIV INFECTIONK23AG000826 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JUSTICE, AMY CAROLINE · 1998 to 2002
$456k
The Impact of Incarceration and Substance Abuse on HIV-Infected VeteransR03DA031592 · NIDA · YALE UNIVERSITY · PI WANG, EMILY AI-HUA · 2012 to 2013
$326k
NCATS NIH HHS UL1 TR000142NCRR NIH HHS UL1 RR024139NHLBI NIH HHS K23 HL103720NIAAA NIH HHS U01 AA013566NIAAA NIH HHS U01 AA020790NIAAA NIH HHS U01 AA 13566NIAAA NIH HHS U10 AA013566NIAAA NIH HHS U10 AA 13566NIAAA NIH HHS U24 AA020794NIA NIH HHS K23 AG00826NIDA NIH HHS 1R03DA031592NIDA NIH HHS R03 DA031592
6 · The paper itself

Abstract

BACKGROUND AND

objectivesOne in seven HIV-infected individuals is incarcerated each year. We used data from the Veterans Aging Cohort Study (VACS) to explore the relationship between incarceration and HIV disease outcomes and evaluate potential mediators of this relationship.

methodsHIV disease outcomes included: low CD4 counts (<200 cells/mL), detectable viral RNA loads (>500 copies/mL), and the VACS Index score. We performed a mediation analysis among 1,591 HIV-infected patients to examine whether unhealthy alcohol use, drug use, primary care engagement, or antiretroviral adherence mediated observed associations.

resultsAmong 1,591 HIV-infected patients, 47% reported having a history of incarceration. In multivariate analyses, a history of incarceration was associated with a higher VACS Index score (β 2.47, 95% CI 0.52-4.43). Mediation analysis revealed that recent drug use attenuated the association by 22% (β 1.93, 95% CI -0.06, 3.91) while other proposed mediators did not. CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Improving access to drug treatment when incarcerated and upon release may be an important target to improving the health of HIV-infected individuals with a history of incarceration. (Am J Addict 2015;24:178-184).

Indexed as

Drug MonitoringAdultAnti-HIV AgentsCohort StudiesCriminalsFemaleHIV InfectionsHumansMaleMiddle AgedPrimary Health CarePrisonersSubstance-Related DisordersTreatment OutcomeUnited StatesVeteransAnti-HIV Agents

Identifiers

PMID25662297
PMCPMC4397180
OpenAlexW2166696765

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.