Evidence map›Paper›PMID 25662262›Full record

ReviewCurrent topics in developmental biology2015

Molecular control of the neural crest and peripheral nervous system development.

Jason M Newbern

Open access · greenAbstract readReview
In one paragraph

Review in Current topics in developmental biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Loss of Twist1 leads to disruption of ciliary length, endocytic vesicle dynamics, and cell-cell junctions during neural tube formation.Developmental dynamics : an official publication of the American Association of Anatomists · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Neural crest cells as a source of microevolutionary variation.Seminars in cell & developmental biology · 2023
    Review
  11. Review
  12. Myelin Biology.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jason M NewbernSchool of Life Sciences, Arizona State University, Tempe, Arizona, USA. Electronic address: jason.newbern@asu.edu.
Arizona State University · US

Funding

ERK/MAPK regulation of cortical inhibitory interneuronsR00NS076661 · NINDS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI NEWBERN, JASON MARSHALL · 2013 to 2015
$726k
NINDS NIH HHS R00 NS076661NINDS NIH HHS R00-NS076661
6 · The paper itself

Abstract

A transient and unique population of multipotent stem cells, known as neural crest cells (NCCs), generate a bewildering array of cell types during vertebrate development. An attractive model among developmental biologists, the study of NCC biology has provided a wealth of knowledge regarding the cellular and molecular mechanisms important for embryogenesis. Studies in numerous species have defined how distinct phases of NCC specification, proliferation, migration, and survival contribute to the formation of multiple functionally distinct organ systems. NCC contributions to the peripheral nervous system (PNS) are well known. Critical developmental processes have been defined that provide outstanding models for understanding how extracellular stimuli, cell-cell interactions, and transcriptional networks cooperate to direct cellular diversification and PNS morphogenesis. Dissecting the complex extracellular and intracellular mechanisms that mediate the formation of the PNS from NCCs may have important therapeutic implications for neurocristopathies, neuropathies, and certain forms of cancer.

Indexed as

Models, BiologicalAnimalsCell MovementNerve Growth FactorsNeural CrestNeurogenesisPeripheral Nervous SystemSignal TransductionVertebratesNerve Growth FactorsGliaNerveSchwann cellSensory neuronSignal transduction

Identifiers

PMID25662262
PMCPMC4517674
OpenAlexW2398405513

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.