ReviewRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo
[Vitamin D deficiency in pregnancy and its impact on the fetus, the newborn and in childhood].
Review in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Efficacy of vitamin D supplementation on the incidence of preeclampsia: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- Effect of maternal vitamin D status on risk of adverse birth outcomes: a systematic review and dose-response meta-analysis of observational studies.European journal of nutrition · 2022Pooled it
- Supplementation of Vitamin D in the Postdelivery Period of Women with Previous Gestational Diabetes Mellitus: Systematic Review and Meta-Analysis of Randomized Trials.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2021Pooled it
- Association Between Vitamin D Supplementation During Pregnancy and Offspring Growth, Morbidity, and Mortality: A Systematic Review and Meta-analysis.JAMA pediatrics · 2018Pooled it
- Vitamin D Deficiency in Preclinical Medical Students: Neuroendocrine, Cognitive, and Immune Effects.Cureus · 2026Review
- Association of Fish Consumption with the Omega-3 Index and Vitamin D Status among Adolescent Females in the Southwest Coastal Zone of Bangladesh.The Journal of nutrition · 2026Article
- Vitamin D status during pregnancy and child neurocognitive functioning at 4 Years.Pediatric research · 2026Article
- Umbilical Cord Biomarkers of Nutritional and Metabolic Status in Neonates with Intrauterine Growth Restriction.Journal of clinical medicine · 2026Review
- Is there a correlation between the severity of symptoms and vitamin D levels in pregnancy with hyperemesis gravidarum?Turkish journal of obstetrics and gynecology · 2025Article
- Effects of Maternal Vitamin D Levels on Prematurity: Feasibility Study in a Multicenter Observational Pilot.Nutrients · 2025Observational
- The relationship between number of pregnancies and serum 25-hydroxyvitamin D levels in women with a prior pregnancy: a cross - sectional analysis, machine learning - based prediction model, and SHAP - assisted feature importance evaluation.Frontiers in endocrinology · 2025Article
- Harnessing behavioral interventions to enhance micronutrient intake in pregnancy: A comprehensive review.Journal of education and health promotion · 2025Review
- Vitamin D and thyroid function of pregnant women in a sunny region: is there any connection?Revista da Associacao Medica Brasileira (1992) · 2025Article
- Vitamin D Deficiency and Maternal Diseases as Risk Factors for the Development of Macrosomia in Newborns.Children (Basel, Switzerland) · 2024Article
- Review
- Effects of vitamin D levels during pregnancy on prematurity: a systematic review protocol.BMJ open · 2024Article
- How effective is public health policy in Scotland on vitamin D deficiency during pregnancy?Public health nutrition · 2023Article
- Vitamin D Supplementation and Sun Exposure Maintain Blood Pressures of Pregnant Women and Increase Birth Weight in a Randomized Controlled Trial.Iranian journal of public health · 2023Article
- Review
- Active vitamin D increases myogenic differentiation in C2C12 cells via a vitamin D response element on the myogenin promoter.Frontiers in physiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveVitamin D deficiency (VDD) in pregnant women and their children is an important health problem with severe consequences for the health of both. Thus, the objectives of this review were to reassess the magnitude and consequences of VDD during pregnancy, lactation and infancy, associated risk factors, prevention methods, and to explore epigenetic mechanisms in early fetal life capable of explaining many of the non-skeletal benefits of vitamin D (ViD). DATA SOURCE: Original and review articles, and consensus documents with elevated level of evidence for VDD-related clinical decisions on the health of pregnant women and their children, as well as articles on the influence of ViD on epigenetic mechanisms of fetal programming of chronic diseases in adulthood were selected among articles published on PubMed over the last 20 years, using the search term VitD status, in combination with Pregnancy, Offspring health, Child outcomes, and Programming. DATA SYNTHESIS: The following items were analyzed: ViD physiology and metabolism, risk factors for VDD and implications in pregnancy, lactation and infancy, concentration cutoff to define VDD, the variability of methods for VDD detection, recommendations on ViD replacement in pregnant women, the newborn and the child, and the epigenetic influence of ViD.
conclusionsVDD is a common condition among high-risk pregnant women and their children. The routine monitoring of serum 25(OH)D3 levels in antenatal period is mandatory. Early preventive measures should be taken at the slightest suspicion of VDD in pregnant women, to reduce morbidity during pregnancy and lactation, as well as its subsequent impact on the fetus, the newborn and the child.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.