Evidence map›Paper›PMID 25661697›Full record

ArticleDrug and alcohol dependence2015

Comorbidity and temporal relations of alcohol and cannabis use disorders from youth through adulthood.

Susan C Duncan, Jeff M Gau, Richard F Farmer, John R Seeley, Derek B Kosty, Peter M Lewinsohn

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Adult Psychiatric, Substance, and Functional Outcomes of Different Definitions of Early Cannabis Use.Journal of the American Academy of Child and Adolescent Psychiatry · 2022
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Interactions Between Alcohol and the Endocannabinoid System.Alcoholism, clinical and experimental research · 2020
    Review
  12. Article
  13. Article
  14. Article
  15. Associations Between Marijuana Use Trajectories and Educational and Occupational Success in Young Adulthood.Prevention science : the official journal of the Society for Prevention Research · 2019
    Article
  16. Article
  17. Article
  18. The natural history of substance use disorders.Current opinion in psychiatry · 2016
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Susan C DuncanOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403-2536, USA. Electronic address: sued@ori.org.
Jeff M GauOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403-2536, USA.
Richard F FarmerOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403-2536, USA.
John R SeeleyOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403-2536, USA.
Derek B KostyOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403-2536, USA.
Peter M LewinsohnOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403-2536, USA.
Oregon Research Institute · US

Funding

Risk for Substance Use Disorders and Comorbid ConditionsR01DA012951 · NIDA · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 2000 to 2004
$3.3M
Natural Course of Cannabis Use Disorders from Childhood Through Early AdulthoodR01DA032659 · NIDA · OREGON RESEARCH INSTITUTE · PI FARMER, RICHARD FRANCIS, SEELEY, JOHN R · 2012 to 2013
$458k
Natural Course and Developmental Trajectories of Alcohol Use DisordersR01AA020968 · NIAAA · OREGON RESEARCH INSTITUTE · PI FARMER, RICHARD FRANCIS, SEELEY, JOHN R · 2012 to 2013
$406k
NATURAL HISTORY OF DEPRESSION IN ADOLESCENTSR01MH050522 · NIMH · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 1993 to 2001
$121k
ADOLESCENT DEPRESSION: PREVALENCE &PSYCHOSOCIAL ASPECTSR01MH040501 · NIMH · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 1986 to 1990
–
NIAAA NIH HHS R01 AA020968NIAAA NIH HHS R01AA020968NIDA NIH HHS DA12951NIDA NIH HHS R01 DA012951NIDA NIH HHS R01 DA032659NIDA NIH HHS R01DA032659NIMH NIH HHS R01 MH040501NIMH NIH HHS R01 MH050522
6 · The paper itself

Abstract

backgroundAlcohol and cannabis are among the most widely used and abused drugs in industrialized societies. Investigations of patterns in comorbidity and temporal sequencing between alcohol use disorders (AUDs) and cannabis use disorders (CUDs) from childhood to adulthood are important for understanding the etiologies of these disorders.

methodsThe sample comprised 816 individuals (59% male, 89% white). Dichotomous measures indicated whether or not a participant was in an AUD or CUD episode during three developmental periods-youth (childhood through adolescence), early adulthood, and adulthood. Structural equation modeling was used to determine relations between AUDs and CUDs across the three developmental periods, and to test for gender differences.

resultsConcurrent associations between AUD and CUD were significant. Both AUD and CUD in previous developmental periods significantly predicted the same substance disorders in subsequent periods. Cross-lagged paths from youth AUD to young adult CUD and youth CUD to young adult AUD were both significant. However, only the cross-lagged path from youth CUD to adult AUD was significant. The cross-lagged paths from young adult AUD to adult CUD and young adult CUD to adult AUD were both nonsignificant. Males and females were mostly similar with only three differences found between genders.

conclusionsComorbidity of AUDs and CUDs was evident from youth through adulthood but the strength of the relationship lessened in adulthood. Temporal sequencing influences of AUDs and CUDs on each other were similar in youth and adulthood but not young adulthood. Same substance stability was greatest in adulthood.

Indexed as

AdolescentAdultAgingAlcoholismData Interpretation, StatisticalFemaleHumansMaleMarijuana AbuseModels, StatisticalOregonPsychiatric Status Rating ScalesRural PopulationSex CharacteristicsUrban PopulationYoung AdultAlcohol use disordersCannabis use disordersComorbidityGender differencesYoung adulthoodYouth

Identifiers

PMID25661697
PMCPMC4361280
OpenAlexW2004544623

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.