Evidence map›Paper›PMID 25661638›Full record

ArticleInternational journal of surgery case reports2015

Thyroidectomy in a two-year old for graves' disease.

Baddr A Shakhsheer, Brian Bordini, Layth Abdulrasool, Raymon Grogan, Edwin Kaplan

Open access · goldAbstract read
In one paragraph

Article in International journal of surgery case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Pediatric Graves' Disease: Surgical Interventions in a Single Institution - A Comprehensive Case Series.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  2. Graves' disease in a five-month-old boy with an unusual treatment course.Journal of pediatric endocrinology & metabolism : JPEM · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Baddr A ShakhsheerDepartment of Surgery, Endocrine Surgery Research Program, The University of Chicago, 5841 S Maryland Avenue, MC 6040, Chicago, IL 60637, USA. Electronic address: Baddr.Shakhsheer@uchospitals.edu.
Brian BordiniAcademic Endocrinology, 1315 Macom Drive, Suite 007, Naperville, IL 60564, USA.
Layth AbdulrasoolDepartment of Surgery, Endocrine Surgery Research Program, The University of Chicago, 5841 S Maryland Avenue, MC 6040, Chicago, IL 60637, USA.
Raymon GroganDepartment of Surgery, Endocrine Surgery Research Program, The University of Chicago, 5841 S Maryland Avenue, MC 6040, Chicago, IL 60637, USA.
Edwin KaplanDepartment of Surgery, Endocrine Surgery Research Program, The University of Chicago, 5841 S Maryland Avenue, MC 6040, Chicago, IL 60637, USA.
University of Chicago · US

Funding

Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
Developing an Oncology Workforce for the 21st Century - Renewal 01K12CA139160 · NCI · UNIVERSITY OF CHICAGO · PI OLOPADE, OLUFUNMILAYO F., SMITH, SONALI · 2010 to 2024
$10.6M
NCATS NIH HHS UL1 TR000430NCI NIH HHS K12 CA139160
6 · The paper itself

Abstract

introductionThe most common cause of hyperthyroidism in children is graves' disease - an autoimmune disorder in which antibodies stimulate the thyrotropin receptor to signal growth thyroid gland by increasing thyroid hormone synthesis and release. It can be treated with medical therapy, radioactive iodine, or surgery. PRESENTATION OF CASE: JD was a two year old male who presented with severe diarrhea and diffuse neck enlargement. Laboratory work up was consistent with graves' disease. DISCUSSION: Despite maximal outpatient and inpatient treatment with methimazole, atenolol, prednisone, and SSKI, he suffered persistent thyrotoxicosis. He underwent near-total thyroidectomy without complication.

conclusionThis case is notable as it may represent the youngest patient in the literature who has undergone thyroidectomy for graves' disease.

Indexed as

ChildrenGraves’HyperthyroidismNear total thyroidectomyThyroidectomy

Identifiers

PMID25661638
PMCPMC4354700
OpenAlexW2026629922

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.