ArticleMolecular cell2015
The molecular timeline of a reviving bacterial spore.
Article in Molecular cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
70 citing papers in PubMed, 140 citations in OpenAlex.
- Article
- Nutrient-induced germination of Bacillus subtilis spores exhibiting shared metabolic profiles in both TSB and AGFK media.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Microbial Community multi-omic analysis of marsh sediment post crustacean shell compost enrichment: pathogen emergence and community response.bioRxiv : the preprint server for biology · 2026Article
- Positive relationship between substrate-induced respiration rate and translationally active bacterial counts in soil.mSystems · 2026Article
- Advances in understanding the Clostridial spore inner membrane.Archives of microbiology · 2026Review
- The Impact of Production Technology on the Quality of Potato Spirit.Molecules (Basel, Switzerland) · 2025Article
- Aerosolization AffectsMicroorganisms · 2025Article
- The Functional Network of PrkC and Its Interaction Proteins inMicroorganisms · 2025Article
- Effects of Aqua-Glycerol Uptake Facilitator Protein GlpF on Spore Germination ofFoods (Basel, Switzerland) · 2025Article
- Recent progress in proteins regulating the germination ofJournal of bacteriology · 2025Review
- Hallmarks of DNA replication stress responses in Escherichia coli and Bacillus subtilis.FEMS microbiology reviews · 2025Review
- Translation in Bacillus subtilis is spatially and temporally coordinated during sporulation.Nature communications · 2024Article
- Resuscitation of viable but nonculturable bacteria promoted by ATP-mediated NADJournal of advanced research · 2024Article
- Biocomposite thermoplastic polyurethanes containing evolved bacterial spores as living fillers to facilitate polymer disintegration.Nature communications · 2024Article
- Processing of stalled replication forks in Bacillus subtilis.FEMS microbiology reviews · 2024Review
- Article
- A unique sigma/anti-sigma system in the actinomycete Actinoplanes missouriensis.Nature communications · 2023Article
- Inactivation Effect of Germination Combined with Cold Plasma Treatment onFoods (Basel, Switzerland) · 2023Article
- Therapeutic potential ofmSphere · 2023Article
- Giving a signal: how protein phosphorylation helps Bacillus navigate through different life stages.FEMS microbiology reviews · 2023Review
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The bacterial spore can rapidly convert from a dormant to a fully active cell. Here we study this remarkable cellular transition in Bacillus subtilis and reveal the identity of the newly synthesized proteins throughout spore revival. Our analysis uncovers a highly ordered developmental program that correlates with the spore morphological changes and reveals the spatial and temporal molecular events fundamental to reconstruct a cell. As opposed to current knowledge, we found that translation takes place during the earliest revival event, termed germination, a process hitherto considered to occur without the need for any macromolecule synthesis. Furthermore, we demonstrate that translation is required for execution of germination and relies on the bona fide translational factors RpmE and Tig. Our study sheds light on the spore revival process and on the vital building blocks underlying cellular awakening, thereby paving the way for designing new antimicrobial agents to eradicate spore-forming pathogens.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.