Evidence map›Paper›PMID 25661473›Full record

ReviewThe Lancet. Infectious diseases2015

The development of global vaccine stockpiles.

Catherine Yen, Terri B Hyde, Alejandro J Costa, Katya Fernandez, John S Tam, Stéphane Hugonnet, Anne M Huvos, Philippe Duclos, Vance J Dietz, Brenton T Burkholder

Abstract readReview
In one paragraph

Review in The Lancet. Infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Monkeypox Virus Infections in Humans.Clinical microbiology reviews · 2022
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. The evolution and future of influenza pandemic preparedness.Experimental & molecular medicine · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Catherine YenGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: cyen@cdc.gov.
Terri B HydeGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Alejandro J CostaPandemic and Epidemic Diseases Department, WHO, Geneva, Switzerland.
Katya FernandezPandemic and Epidemic Diseases Department, WHO, Geneva, Switzerland.
John S TamDepartment of Immunization, Vaccines and Biologicals, WHO, Geneva, Switzerland.
Stéphane HugonnetPandemic and Epidemic Diseases Department, WHO, Geneva, Switzerland.
Anne M HuvosPandemic and Epidemic Diseases Department, WHO, Geneva, Switzerland.
Philippe DuclosDepartment of Immunization, Vaccines and Biologicals, WHO, Geneva, Switzerland.
Vance J DietzGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Brenton T BurkholderWHO, Bangkok, Thailand.

Funding

Intramural CDC HHS CC999999World Health Organization 001
6 · The paper itself

Abstract

Global vaccine stockpiles, in which vaccines are reserved for use when needed for emergencies or supply shortages, have effectively provided countries with the capacity for rapid response to emergency situations, such as outbreaks of yellow fever and meningococcal meningitis. The high cost and insufficient supply of many vaccines, including oral cholera vaccine and pandemic influenza vaccine, have prompted discussion on expansion of the use of vaccine stockpiles to address a wider range of emerging and re-emerging diseases. However, the decision to establish and maintain a vaccine stockpile is complex and must take account of disease and vaccine characteristics, stockpile management, funding, and ethical concerns, such as equity. Past experience with global vaccine stockpiles provide valuable information about the processes for their establishment and maintenance. In this Review we explored existing literature and stockpile data to discuss the lessons learned and to inform the development of future vaccine stockpiles.

Indexed as

Strategic StockpileVaccinesCommunicable Disease ControlCommunicable Diseases, EmergingGlobal HealthHumansVaccines

Identifiers

PMID25661473
PMCPMC4712379

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.