SynthesisMedical principles and practice : international journal of the Kuwait University, Health Science Centre2015
Resin infiltration of non-cavitated caries lesions: a systematic review.
Synthesis in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Do systematic reviews of non- and micro-invasive treatment for caries lesions in children and adolescents adhere to the PRISMA reporting guidelines? A meta-research.Evidence-based dentistry · 2026Pooled it
- Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the Application of Infiltrative Resins: Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Infiltration and sealing for managing non-cavitated proximal lesions: a systematic review and meta-analysis.BMC oral health · 2021Pooled it
- Best clinical practice guidance for management of early caries lesions in children and young adults: an EAPD policy document.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2016Guideline
- The Effect of Resin Infiltration on the Progression of Proximal Caries Lesions: A Randomized Clinical Trial.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2020Trial
- Combined Near-Infrarred Light Transillumination and Direct Digital Radiography Increases Diagnostic In Approximal Caries.Scientific reports · 2019Trial
- Comparative evaluation of Icon® resin infiltration and Clinpro™ XT varnish on colour and fluorescence changes of white spot lesions: a randomized controlled trial.Progress in orthodontics · 2019Trial
- Efficacy of resin infiltration of proximal caries in primary molars: 1-year follow-up of a split-mouth randomized controlled clinical trial.Clinical oral investigations · 2018Trial
- Proximal carious lesions infiltration-a 3-year follow-up study of a randomized controlled clinical trial.Clinical oral investigations · 2018Trial
- Resin Infiltration in the Conservative Management of Incipient Dental Caries: An Evidence-Based Review.Journal of clinical medicine · 2026Review
- Influence of Tooth Whitening After Resin Infiltration on the Shear Bond Strength of Orthodontic Brackets.The journal of adhesive dentistry · 2026Article
- Polyacrylic Acid concentrations on biomimetic remineralization in artificial enamel lesions.BMC oral health · 2026Article
- Efficacy of Resin Infiltrants in Non-Cavitated Occlusal Carious Lesions: A Systematic Review.Journal of clinical medicine · 2026Review
- Resin Infiltration for Anterior Teeth Affected by Molar Incisor Hypomineralization in Children and Adolescents: A Clinical Study of Color Masking, Sensitivity, and Aesthetic Perception: A Prospective Single-Arm Interventional Clinical Study.Children (Basel, Switzerland) · 2026Article
- Bioactive and Ion-releasing materials in minimum intervention dentistry: a clinical pathway from prevention to restorative treatment.Frontiers in dental medicine · 2026Article
- Effect of resin infiltration system and pit-fissure sealant on white spot lesion: AnBioinformation · 2025Article
- Overdiagnosis of dental caries in South Korea: a pseudo-patient study.BMC oral health · 2024Article
- Article
- Resin Infiltration for the Esthetic Improvement of Dental Fluorosis and White Spots: A Case Report.Cureus · 2024Article
- Effect of the use of remineralization agents before resin infiltration on the treatment of initial enamel lesions: an in-vitro study.BMC oral health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this systematic review was to evaluate the in vivo scientific evidence of the ability of resin infiltration (RI) to arrest non-cavitated caries lesions. MATERIALS AND
methodsThe PubMed database was searched for randomized controlled trials that evaluated the in vivo effect of RI versus placebo or other preventive treatment on the progression of caries lesions. The keywords used were 'resin infiltration, dental caries', 'resin infiltration, carious lesions', 'resin infiltration, caries lesions', 'caries infiltration' and 'Icon DMG' with the 'clinical trial' filter activated. Among the 14 articles originally identified with these keywords, only 4 (related to 3 different in vivo studies) were included for this review.
resultsAll 4 articles reported on proximal caries lesions. One study had been conducted on 48 high-caries-risk children while the other 3 (n = 22, 22 and 39, respectively) concerned moderate- and low-caries-risk adolescents and adults. The quality of the studies was assessed to be high with respect to randomization, split-mouth design and blinding. All the included studies showed significant differences in caries progression between test and control/placebo groups, indicating that RI may inhibit the carious process.
conclusionThis systematic review revealed that RI appeared to be an effective method to arrest the progression of non-cavitated caries lesions. Additional, long-term studies are required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.