ArticleJACC. Heart failure2015
Intravenous fluids in acute decompensated heart failure.
Article in JACC. Heart failure, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 41 citations in OpenAlex.
- Perioperative fluid management in older trauma patients : Practical algorithms and statement of the Working Group on Geriatric Traumatology of the German Society for Geriatrics.Zeitschrift fur Gerontologie und Geriatrie · 2026Review
- Appropriateness of intravenous fluid prescriptions in hospitalised patients: a point prevalence study.International journal of clinical pharmacy · 2025Article
- Fluid Restriction for Patients with Heart Failure: Current Evidence and Future Perspectives.Journal of personalized medicine · 2024Review
- Increased risk of hip fracture mortality associated with intraoperative hypotension in elderly hip fracture patients is related to under resuscitation.Journal of clinical orthopaedics and trauma · 2022Article
- Effects of Metolazone Administration on Congestion, Diuretic Response and Renal Function in Patients with Advanced Heart Failure.Journal of clinical medicine · 2021Article
- Medical management of pediatric heart failure.Cardiovascular diagnosis and therapy · 2021 · on this mapReview
- Equipoise in Appropriate Initial Volume Resuscitation for Patients in Septic Shock With Heart Failure: Results of a Multicenter Clinician Survey.Journal of intensive care medicine · 2020Article
- A Standardized and Comprehensive Approach to the Management of Cardiogenic Shock.JACC. Heart failure · 2020Review
- Iatrogenic Decompensated Heart Failure.Current heart failure reports · 2020Review
- Variability in usual care fluid resuscitation and risk-adjusted outcomes for mechanically ventilated patients in shock.Critical care (London, England) · 2020Article
- Acute adverse events in cardiac MR imaging with gadolinium-based contrast agents: results from the European Society of Cardiovascular Radiology (ESCR) MRCT Registry in 72,839 patients.European radiology · 2019Article
- Renal Effects of Intensive Volume Removal in Heart Failure Patients With Preexisting Worsening Renal Function.Circulation. Heart failure · 2019Article
- Hyponatremia in Heart Failure: Pathogenesis and Management.Current cardiology reviews · 2019Review
- Acute kidney injury and 'nephrotoxins': mind your language.Clinical medicine (London, England) · 2018Review
- Plasma Volume and Renal Function Predict Six-Month Survival after Hospitalization for Acute Decompensated Heart Failure.Cardiorenal medicine · 2017Article
- Learning to prescribe intravenous fluids: A scoping review.Perspectives on medical education · 2017Article
- Current Management of Hyponatremia in Acute Heart Failure: A Report From the Hyponatremia Registry for Patients With Euvolemic and Hypervolemic Hyponatremia (HN Registry).Journal of the American Heart Association · 2017Observational
- Hypochloraemia is strongly and independently associated with mortality in patients with chronic heart failure.European journal of heart failure · 2016Article
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesThis study sought to determine the use of intravenous fluids in the early care of patients with acute decompensated heart failure (HF) who are treated with loop diuretics.
backgroundIntravenous fluids are routinely provided to many hospitalized patients.
methodsWe conducted a retrospective cohort study of patients admitted with HF to 346 hospitals from 2009 to 2010. We assessed the use of intravenous fluids during the first 2 days of hospitalization. We determined the frequency of adverse in-hospital outcomes. We assessed variation in the use of intravenous fluids across hospitals and patient groups.
resultsAmong 131,430 hospitalizations for HF, 13,806 (11%) were in patients treated with intravenous fluids during the first 2 days. The median volume of administered fluid was 1,000 ml (interquartile range: 1,000 to 2,000 ml), and the most commonly used fluids were normal saline (80%) and half-normal saline (12%). Demographic characteristics and comorbidities were similar in hospitalizations in which patients did and did not receive fluids. Patients who were treated with intravenous fluids had higher rates of subsequent critical care admission (5.7% vs. 3.8%; p < 0.0001), intubation (1.4% vs. 1.0%; p = 0.0012), renal replacement therapy (0.6% vs. 0.3%; p < 0.0001), and hospital death (3.3% vs. 1.8%; p < 0.0001) compared with those who received only diuretics. The proportion of hospitalizations that used fluid treatment varied widely across hospitals (range: 0% to 71%; median: 12.5%).
conclusionsMany patients who are hospitalized with HF and receive diuretics also receive intravenous fluids during their early inpatient care, and the proportion varies among hospitals. Such practice is associated with worse outcomes and warrants further investigation.
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