Evidence map›Paper›PMID 25660551›Full record

SynthesisSocial psychiatry and psychiatric epidemiology2015

Schizophrenia and other psychotic disorders in Caribbean-born migrants and their descendants in England: systematic review and meta-analysis of incidence rates, 1950-2013.

A Tortelli, A Errazuriz, T Croudace, C Morgan, R M Murray, P B Jones, A Szoke, J B Kirkbride

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Social psychiatry and psychiatric epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Perceived discrimination and psychosis: a systematic review of the literature.Social psychiatry and psychiatric epidemiology · 2019
    Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Exploring causal mechanisms of psychosis risk.Neuroscience and biobehavioral reviews · 2024
    Review
  8. Review
  9. Stress, Environment and Early Psychosis.Current neuropharmacology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Ethnic disparities in psychotic experiences explained by area-level syndemic effects.The British journal of psychiatry : the journal of mental science · 2020
    Article
  14. Article
  15. Migration, ethnicity and psychoses: evidence, models and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2019
    Article
  16. Non-Genetic Factors in Schizophrenia.Current psychiatry reports · 2019
    Review
  17. Article
  18. Review
  19. What causes psychosis? An umbrella review of risk and protective factors.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

A TortelliINSERM, U955, Equipe 15, Créteil, 94000, France.
A Errazuriz
T Croudace
C Morgan
R M Murray
P B Jones
A Szoke
J B Kirkbride
King's College London · GBUniversity of Cambridge · GBAssistance Publique – Hôpitaux de Paris · FRInserm · FRSt Charles Hospital · GBUniversity of Dundee · GB

Funding

Medical Research Council G0001354Wellcome Trust 101272
6 · The paper itself

Abstract

purposeIncreased risk of schizophrenia and other psychotic disorders among black Caribbean migrants and their descendants have been described since the 1960s. It remains unclear whether this risk varies over time, between rural and urban areas, or according to methodological artefact.

methodsWe conducted a systematic review of the incidence of adult-onset psychotic disorders in black Caribbean groups relative to the baseline population in England, published 1950-2013. Subject to sufficient data (N ≥ 5) we used random effects meta-analyses to estimate pooled incidence rates (IR) and rate ratios (IRR) of seven psychotic disorder outcomes, and meta-regression to inspect whether any variation was attributable to study-level methodological features, including case ascertainment, denominator reliability, choice of baseline population and study quality.

resultsEighteen studies met inclusion for review. Sixteen demonstrated statistically significant elevated incidence rates in the black Caribbean group, present across all major psychotic disorders, including schizophrenia and bipolar disorder. Methodological quality increased over time (p = 0.01), but was not associated with estimated IR or IRR. For schizophrenia (N = 11 studies) the pooled IRR in the black Caribbean group was 4.7 (95 % CI 3.9-5.7) relative to the baseline; no evidence of publication bias was observed. We found weak evidence to suggest schizophrenia IRRs were smaller from studies in more urban settings (odds ratio 0.98; 95 % CI 0.96-1.00; p = 0.06).

conclusionsHigher incidence rates of psychotic disorders have been present for more than 60 years amongst black Caribbean ethnic groups in England, despite improved study methodologies over time. Aetiological explanations appear to more parsimoniously account for this excess than methodological biases.

Indexed as

Transients and MigrantsBlack PeopleCaribbean RegionEnglandHumansIncidencePsychotic DisordersReproducibility of ResultsRiskSchizophrenia

Identifiers

PMID25660551
PMCPMC4464051
OpenAlexW1981669174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.