Evidence map›Paper›PMID 25660265›Full record

ReviewJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2015

Ebola and Marburg haemorrhagic fever.

V Rougeron, H Feldmann, G Grard, S Becker, E M Leroy

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 148 citations in OpenAlex.

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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 4 countries.

V RougeronLaboratoire MiVEGEC, UMR IRD 224 CNRS 5290 UMI, 911 Av. Agropolis, 34394 Montpellier, Cedex 5, France; International Center for Medical Research of Franceville, BP769, Franceville, Gabon. Electronic address: rougeron.virginie@gmail.com.
H FeldmannLaboratory of Virology, Division of Intramural Research, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT, USA.
G GrardInternational Center for Medical Research of Franceville, BP769, Franceville, Gabon.
S BeckerInstitut für Virologie, Philipps-Universität Marburg, Hans-Meerwein-Str. 2, Marburg 35037, Germany.
E M LeroyLaboratoire MiVEGEC, UMR IRD 224 CNRS 5290 UMI, 911 Av. Agropolis, 34394 Montpellier, Cedex 5, France; International Center for Medical Research of Franceville, BP769, Franceville, Gabon.
Agropolis International · FRCentre International de Recherches Médicales de Franceville · GAMaladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle · FRNational Institute of Allergy and Infectious Diseases · USPhilipps University of Marburg · DE

Funding

Viral Hemorrhagic Fevers: Disease Modeling and TransmissionZIAAI001089 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI FELDMANN, HEINRICH · 2009 to 2025
$50.7M
Intramural NIH HHS Z99 AI999999Intramural NIH HHS ZIA AI001089
6 · The paper itself

Abstract

Ebolaviruses and Marburgviruses (family Filoviridae) are among the most virulent pathogens for humans and great apes causing severe haemorrhagic fever and death within a matter of days. This group of viruses is characterized by a linear, non-segmented, single-stranded RNA genome of negative polarity. The overall burden of filovirus infections is minimal and negligible compared to the devastation caused by malnutrition and other infectious diseases prevalent in Africa such as malaria, dengue or tuberculosis. In this paper, we review the knowledge gained on the eco/epidemiology, the pathogenesis and the disease control measures for Marburg and Ebola viruses developed over the last 15 years. The overall progress is promising given the little attention that these pathogen have achieved in the past; however, more is to come over the next decade given the more recent interest in these pathogens as potential public and animal health concerns. Licensing of therapeutic and prophylactic options may be achievable over the next 5-10 years.

Indexed as

Hemorrhagic Fever, EbolaMarburg Virus DiseaseAfricaAnimalsDisease OutbreaksEbolavirusHumansMarburgvirusPrevalence

Identifiers

PMID25660265
PMCPMC11080958
OpenAlexW2022701206

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.