SynthesisMedical science monitor : international medical journal of experimental and clinical research2015
Endobronchial valves in treatment of persistent air leaks: a systematic review of clinical evidence.
Synthesis in Medical science monitor : international medical journal of experimental and clinical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Endobronchial one-way valves for treatment of persistent air leaks: a systematic review.Respiratory research · 2017Pooled it
- Study Protocol of the Endobronchial VAlves for Pneumothorax to Reduce Admission Time (EVAPoRATe) Pilot Multicentre Randomised Clinical Trial.Respirology case reports · 2026Trial
- Endoluminal approaches to postoperative air leaks.Journal of thoracic disease · 2026Review
- Bronchoperitoneal fistula in a patient with pneumatosis Cystoides intestinalis: a diagnostic challenge.Oxford medical case reports · 2026Article
- Transforming pulmonary care with applications of endobronchial valves beyond emphysema: a narrative review.Annals of translational medicine · 2025Review
- Lung-Mimetic Hydrofoam Sealant to Treat Pulmonary Air Leak.Advanced healthcare materials · 2024Article
- ERS International Congress 2023: highlights from the Respiratory Intensive Care Assembly.ERJ open research · 2024Article
- Predictors of reoperation after lung volume reduction surgery.Surgical endoscopy · 2024Article
- Intrathoracic negative pressure therapy and/or endobronchial valve for pleural empyema minimal invasive management: case series of thirteen patients and review of the literature.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2020Article
- Management of air leaks post-surgical lung resection.Annals of translational medicine · 2019Review
- Persistent air leak after pulmonary transplantation.BMJ case reports · 2017Article
- Bronchopleural Fistula Resolution with Endobronchial Valve Placement and Liberation from Mechanical Ventilation in Acute Respiratory Distress Syndrome: A Case Series.Case reports in critical care · 2017Article
- The Clinical Significance of Collateral Ventilation.Annals of the American Thoracic Society · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPersistent air leak is one of the most common complications of lung diseases and pulmonary resections. Prolonged hospitalization, increased morbidity, and increased overall treatment costs arise from persistent air leaks. The use of endobronchial valves (EBVs) in the management of air leaks is an important alternative, especially for patients who are not candidates for surgical treatment. MATERIAL/
methodsWe retrieved the included studies by performing a systematic search in PubMed and Scopus databases. The references of the included studies were also hand-searched.
resultsWe retrieved 25 case reports and 3 case series from our literature search. The most common cause of persisting air leaks was spontaneous secondary pneumothorax (12/39, 31%). The left upper lobe (13/39, 33%) and right upper lobe (14/39, 36%) were the most frequent locations of air leaks. Most air leaks treated with EBVs ceased in less than 24 h. Three recurrences of air leak were reported and 2 cases of EBV migration were described. No deaths were reported in correlation with EBVs.
conclusionsEBVs are a minimally invasive therapeutical option that may be suitable for the treatment of persistent air leaks regardless of the initial cause, especially in high-risk patients. Nevertheless, studies with better methodological quality are essential to standardize this technique and to provide more evidence on EBV safety issues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.