Evidence map›Paper›PMID 25659541›Full record

ArticleAfrican journal of paediatric surgery : AJPS

Epidemiology, management and outcome of gastroschisis in Sub-Saharan Africa: Results of an international survey.

Naomi J Wright, Augusto Zani, Niyi Ade-Ajayi

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in African journal of paediatric surgery : AJPS. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03185637 (Paediatric Surgery Across Sub-Saharan Africa), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03185637 completednot on this map

Paediatric Surgery Across Sub-Saharan Africa: A Multi-Centre Prospective Cohort Study

Typeobservational_patient_registrySponsorKing's College LondonRan2016 to 2017Enrolled1,407ConditionsGastroschisis, Anorectal Malformation, Appendicitis, IntussusceptionArmsVarious interventions for each of the conditions.
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Naomi J Wright
Augusto Zani
Niyi Ade-AjayiDepartment of Paediatric Surgery, Kings College Hospital, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim was to compare gastroschisis (GS) epidemiology, management and outcome in low-income countries (LIC) in Sub-Saharan Africa (SSA) with middle- (MIC) and high-income countries (HIC). MATERIALS AND

methodsA 10-question survey was administered at the 2012 Pan-African Paediatric Surgery Association Congress. RESULTS are presented as median (range); differences were analysed using contingency tests.

resultsA total of 82 delegates (28 countries [66 institutions]) were divided into LIC (n = 11), MIC (n = 6) and HIC (n = 11). In LIC, there were fewer surgeons and more patients. LIC reported 22 cases (1-184) GS/institution/year, compared to 12 cases (3-23)/institution/year in MICs and 15 cases (1-100)/institution/year in HICs. Antenatal screening was less readily available in LIC. Access to parenteral nutrition and neonatal intensive care in LIC was 36% and 19%, compared to 100% in HIC. Primary closure rates were similar in LIC and HIC at 58% and 54%, respectively; however, the majority of staged closure utilised custom silos in LIC and preformed silos in HIC. In LIC, mortality was reported as >75% by 61% delegates and 50-75% by 33%, compared to <25% by 100% of HIC delegates (P < 0.0001).

conclusionsGastroschisis is a problem encountered by surgeons in SSA. Mortality is high and resources in many centres inadequate. We propose the implementation of a combined epidemiological research, service delivery training and resource provision programme to help improve our understanding of GS in SSA whilst attempting to improve outcome.

Indexed as

Disease ManagementSurveys and QuestionnairesAfrica South of the SaharaDigestive System Surgical ProceduresFemaleGastroschisisGestational AgeHumansIncidenceInfant, NewbornMale

Identifiers

PMID25659541
PMCPMC4955493

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.