Trial reportJournal of athletic training2015
Blood flow after exercise-induced muscle damage.
Trial report in Journal of athletic training, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Cooling of Lower Extremity Muscles According to Subcutaneous Tissue Thickness.Journal of athletic training · 2019Trial
- Use of Cold-Water Immersion to Reduce Muscle Damage and Delayed-Onset Muscle Soreness and Preserve Muscle Power in Jiu-Jitsu Athletes.Journal of athletic training · 2016Trial
- Impact of a low-intensity exercise prior to infrared thermography measurements on skin temperature under conditions of muscle soreness.Scientific reports · 2026Article
- Skin blood flow and skin temperature 24 h after induced muscle damage.Physiological reports · 2025Article
- Effects of ischaemic post-conditioning on eccentric exercise-induced muscle damage.Biology of sport · 2024Article
- The effect of Liquid ice after high-intensity exercise on muscle function compared to Block ice.Journal of exercise science and fitness · 2022Article
- Relationships between resting blood flow and the indices of muscle damage after eccentric contractions.European journal of applied physiology · 2020Article
- Evaluation of capillary blood volume in the lower limb muscles after exercise by intravoxel incoherent motion.La Radiologia medica · 2020Article
- Metabolic Profiling of Eccentric Exercise-Induced Muscle Damage in Human Urine.Toxicological research · 2018Article
- Update of Contrast-enhanced Ultrasound in Musculoskeletal Medicine: Clinical Perspectives - A Review.Journal of medical ultrasoundReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
contextThe most common modality used to address acute inflammation is cryotherapy. Whereas pain decreases with cryotherapy, evidence that changes occur in perfusion of skeletal muscle is limited. We do not know whether ice attenuates the increases in perfusion associated with acute inflammation.
objectiveTo examine the effects of repeated applications of ice bags on perfusion of the gastrocnemius muscle after an eccentric exercise protocol.
designControlled laboratory study.
settingLaboratory. PATIENTS OR OTHER
participantsEighteen healthy participants (3 men, 15 women; age = 22.2 ± 2.2 years, height = 166.0 ± 11.9 cm, mass = 69.4 ± 25.0 kg). INTERVENTION(S): To induce eccentric muscle damage, participants performed 100 unilateral heel-lowering exercises off a step to the beat of a metronome. A randomized intervention (cryotherapy, sham, control) was applied to the exercised lower extremity immediately after the protocol and again at 10, 24, and 34 hours after the protocol. MAIN OUTCOME MEASURE(S): Baseline perfusion measurements (blood volume, blood flow, and blood flow velocity) were taken using contrast-enhanced ultrasound of the exercised leg. Perfusion was reassessed after the first intervention and 48 hours after the protocol as percentage change scores. Pain was measured with a visual analog scale at baseline and at 10, 24, 34, and 48 hours after the protocol. Separate repeated-measures analyses of variance were used to assess each dependent variable.
resultsWe found no interactions among interventions for microvascular perfusion. Blood volume and blood flow, however, increased in all conditions at 48 hours after exercise (P < .001), and blood flow velocity decreased postintervention from baseline (P = .041). We found a time-by-intervention interaction for pain (P = .009). Visual analog scale scores were lower for the cryotherapy group than for the control group at 34 and 48 hours after exercise.
conclusionsWhereas eccentric muscle damage resulted in increased blood flow, ice did not decrease muscle perfusion 48 hours after exercise. Therefore, ice does not seem to decrease muscle perfusion when blood flow is elevated, as it would be during inflammation.
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