ArticleNature biotechnology2015
Mapping the precision of genome editing.
Article in Nature biotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Design principle of successful genome editing applications using CRISPR-based toolkits.Journal of applied genetics · 2025Review
- RESTRICT-seq enables time-gated CRISPR screens and uncovers novel epigenetic dependencies of SCC resistance.bioRxiv : the preprint server for biology · 2025Article
- Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges.Military Medical Research · 2023Review
- Expanding Gene-Editing Potential in Crop Improvement with Pangenomes.International journal of molecular sciences · 2022Review
- Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System.Molecular therapy. Methods & clinical development · 2020Article
- Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking.Nucleic acids research · 2020Article
- Genome editing for blood disorders: state of the art and recent advances.Emerging topics in life sciences · 2019Article
- Synthetic switch to minimize CRISPR off-target effects by self-restricting Cas9 transcription and translation.Nucleic acids research · 2019Article
- A novel λ integrase-mediated seamless vector transgenesis platform for therapeutic protein expression.Nucleic acids research · 2018Article
- TRH Action Is Impaired in Pituitaries of Male IGSF1-Deficient Mice.Endocrinology · 2017Article
- Genome-wide Specificity of Highly Efficient TALENs and CRISPR/Cas9 for T Cell Receptor Modification.Molecular therapy. Methods & clinical development · 2017Article
- CRISPR-Cas9 technology and its application in haematological disorders.British journal of haematology · 2016Review
- Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity.Molecular cell · 2016Review
- Advances in the Study of Heart Development and Disease Using Zebrafish.Journal of cardiovascular development and disease · 2016Article
- Conservative site-specific and single-copy transgenesis in human LINE-1 elements.Nucleic acids research · 2016Article
- Cell and Gene Therapy for the Beta-Thalassemias: Advances and Prospects.Human gene therapy · 2016Review
- Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq.Genome research · 2016Article
- Genetic treatment of a molecular disorder: gene therapy approaches to sickle cell disease.Blood · 2016Review
- DNA-binding-domain fusions enhance the targeting range and precision of Cas9.Nature methods · 2015Article
- Off-target Effects in CRISPR/Cas9-mediated Genome Engineering.Molecular therapy. Nucleic acids · 2015Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
25658281What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.