ArticleJournal of nephropathology2015
Crystal-induced acute kidney injury due to ciprofloxacin.
Article in Journal of nephropathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 31 citations in OpenAlex.
- Renal Impairment Caused by Tosufloxacin Crystals in an Adult.Internal medicine (Tokyo, Japan) · 2025Article
- Cystine crystal nucleation and decay in the context of cystinuria pathogenesis and treatment.RSC advances · 2024Article
- Overview of Antibiotic-Induced Nephrotoxicity.Kidney international reports · 2023Review
- Overview of Side-Effects of Antibacterial Fluoroquinolones: New Drugs versus Old Drugs, a Step Forward in the Safety Profile?Pharmaceutics · 2023Review
- Chronic Kidney Disease, Urinary Tract Infections and Antibiotic Nephrotoxicity: Are There Any Relationships?Medicina (Kaunas, Lithuania) · 2022Review
- Alkalising agents in urinary tract infections: theoretical contraindications, interactions and synergy.Therapeutic advances in drug safety · 2022Article
- Analysis of Risk Factors for Perioperative Acute Kidney Injury and Management Strategies.Frontiers in medicine · 2021Review
- Mechanisms of antimicrobial-induced nephrotoxicity in children.The Journal of antimicrobial chemotherapy · 2020Review
- Drug-Induced Kidney Stones and Crystalline Nephropathy: Pathophysiology, Prevention and Treatment.Drugs · 2018Review
- Concise Review: Current and Emerging Biomarkers of Nephrotoxicity.Current opinion in toxicology · 2017Article
- Acute kidney injury due to ciprofloxacin for treatment of acute pyelonephritis.Journal of nephropharmacology · 2016Article
- Heroin crystal nephropathy.Clinical kidney journal · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFluoroquinolones are known to cause acute renal failure due to interstitial nephritis. CASE PRESENTATION: Here we present an elderly woman who developed oliguric acute kidney injury (AKI) after receiving oral and intravenous ciprofloxacin in a 48-hour period. Recently, several case reports have been published in the literature regarding the presence of crystals in the urine sediment of patients treated with ciprofloxacin for different types of systemic infections. Ciprofloxacin crystals precipitate in alkaline urine and provoke renal failure through intra-tubular precipitation.
conclusionsConservative measures including intravenous hydration and avoidance of alkalinization of the urine can reverse this condition if applied in time.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.