ArticleBiomedical optics express2015
Detection of cervical cancer based on photoacoustic imaging-the in-vitro results.
Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 44 citations in OpenAlex.
- Feasibility of clinical detection of cervical dysplasia using angle-resolved low coherence interferometry measurements of depth-resolved nuclear morphology.International journal of cancer · 2017Trial
- Recent Advances in Photoacoustic Imaging: Current Status and Future Perspectives.Micromachines · 2024Review
- Photoacoustic clinical applications: Musculoskeletal and abdominal imaging.Zeitschrift fur medizinische Physik · 2023Review
- Application of photoacoustic computed tomography in biomedical imaging: A literature review.Bioengineering & translational medicine · 2023Review
- Photoacoustic tomography reconstruction using lag-based delay multiply and sum with a coherence factor improves in vivo ovarian cancer diagnosis.Biomedical optics express · 2021Article
- Development of Multispectral Optoacoustic Tomography as a Clinically Translatable Modality for Cancer Imaging.Radiology. Imaging cancer · 2020Review
- High-Resolution Photoacoustic Tomography for Early-Stage Cancer Detection and Its Clinical Translation.Radiology. Imaging cancer · 2020Review
- Photoacoustic Imaging in Tissue Engineering and Regenerative Medicine.Tissue engineering. Part B, Reviews · 2020Review
- A Dual-modality Smartphone Microendoscope for Quantifying the Physiological and Morphological Properties of Epithelial Tissues.Scientific reports · 2019Article
- Photoacoustic imaging with low-cost sources; A review.Photoacoustics · 2019Review
- Photoacoustic clinical imaging.Photoacoustics · 2019Review
- State-of-the-Art Preclinical Photoacoustic Imaging in Oncology: Recent Advances in Cancer Theranostics.Contrast media & molecular imaging · 2019Review
- Laser scanning laser diode photoacoustic microscopy system.Photoacoustics · 2018Article
- [Focal zone integral and multiple axial scanning based acoustic resolution photoacoustic microscopy with high lateral resolution in-depth].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2018Article
- Optical techniques for cervical neoplasia detection.Beilstein journal of nanotechnology · 2017Review
- Mixed Total Variation andComputational and mathematical methods in medicine · 2017Article
- Clinical photoacoustic imaging of cancer.Ultrasonography (Seoul, Korea) · 2016Review
- Photoacoustic Imaging in Oncology: Translational Preclinical and Early Clinical Experience.Radiology · 2016Review
- Toward in vivo biopsy of melanoma based on photoacoustic and ultrasound dual imaging with an integrated detector.Biomedical optics express · 2016Article
- Mechanical characterization of intraluminal tissue with phase-resolved photoacoustic viscoelasticity endoscopy.Biomedical optics express · 2015Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In current clinical practice, the diagnosis of cervical cancer (CC) is mainly through the cervical screening followed by a necessary biopsy, but this method is labor consuming and expensive, and can only detect superficial lesions around the external cervical orifice. In contrast, photoacoustic imaging (PAI) is sensitive to the abnormal angiogenesis deep in the biological tissue, and may be capable for the intact scanning both around the external orifice and in cervical canal. In this paper, we for the first time put forward the photoacoustic diagnosis of CC. A total of 30 in-vitro experiments were carried out in this study, and the obtained depth maximum amplitude projection (DMAP) images were analyzed to evaluate the extent of the angiogenesis for different clinical stages of CC. Stronger absorption from the cervical lesions is observed relative to that of normal tissue. Paired t-test indicates that the difference in mean optical absorption (MOA) between normal tissue and cervical lesion has statistical significance with a confidential coefficient of 0.05. Statistical results also show that the MOAs of the cervical lesions are closely related to the severity of CC. These results imply that PAI may have great utility in the clinical diagnosis of CC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.