ArticleBiomedical optics express2015
Stretching of red blood cells using an electro-optics trap.
Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Optical tweezers in biomedical research - progress and techniques.Journal of medicine and life · 2024Review
- Measurement of red blood cell deformability during morphological changes using rotating-glass-plate-based scanning optical tweezers.Biomedical optics express · 2023Article
- Mechanical fatigue of human red blood cells.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Modeling erythrocyte electrodeformation in response to amplitude modulated electric waveforms.Scientific reports · 2018Article
- Continuous-Flow Cell Dipping and Medium Exchange in a Microdevice using Dielectrophoresis.Micromachines · 2018Article
- Dielectrophoresis Testing of Nonlinear Viscoelastic Behaviors of Human Red Blood Cells.Micromachines · 2018Article
- Characterization of biomechanical properties of cells through dielectrophoresis-based cell stretching and actin cytoskeleton modeling.Biomedical engineering online · 2017Article
- Study of in vitro RBCs membrane elasticity with AOD scanning optical tweezers.Biomedical optics express · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The stretching stiffness of Red Blood Cells (RBCs) was investigated using a combination of an AC dielectrophoretic apparatus and a single-beam optical tweezer. The experiments were performed at 10 MHz, a frequency high enough to avoid conductivity losses, but below the second turnover point between positive and negative dielectrophoresis. By measuring the geometrical parameters of single healthy human RBCs as a function of the applied voltage, the elastic modulus of RBCs was determined (µ = 1.80 ± 0.5 µN/m) and compared with similar values of the literature got by other techniques. The method is expected to be an easy-to-use, alternative tool to determine the mechano-elastic properties of living cells, and, on this basis, to distinguish healthy and diseased cells.
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Registered trials
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