Evidence map›Paper›PMID 25657849›Full record

ArticleAging and disease2015

Effect of Aging in the Perception of Health-Related Quality of Life in End-Stage Renal Disease Patients under Online-Hemodiafiltration.

Alexandra Moura, José Madureira, Pablo Alija, João Carlos Fernandes, José Gerardo Oliveira, Martin Lopez, Madalena Filgueiras, Leonilde Amado, Maria Sameiro-Faria, Vasco Miranda and 2 more

Open access · goldAbstract read
In one paragraph

Article in Aging and disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Alexandra MouraInstituto de Ciências da Saúde, Universidade Católica Portuguesa, Porto, Portugal.
José MadureiraClínica de Hemodiálise NefroServe, Barcelos, Portugal.
Pablo AlijaClínica de Hemodiálise NefroServe, Barcelos, Portugal.
João Carlos FernandesClínica de Hemodiálise NefroServe, Viana do Castelo, Portugal.
José Gerardo OliveiraCentro Hospitalar do Porto, Porto, Portugal.
Martin LopezClínica de Hemodiálise de Felgueira, Felgueiras, Portugal.
Madalena FilgueirasClínica de Hemodiálise de Gondomar, Gondomar, Portugal.
Leonilde AmadoClínica de Hemodiálise NephroCare, Maia, Portugal.
Maria Sameiro-FariaClínica de Hemodiálise NephroCare, Maia, Portugal.
Vasco MirandaClínica de Hemodiálise NephroCare, Maia, Portugal.
Alice Santos-SilvaLaboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Portugal ; Instituto de Biologia Molecular e Celular, Universidade do Porto, Portugal.
Elísio CostaLaboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Portugal ; Instituto de Biologia Molecular e Celular, Universidade do Porto, Portugal.
Centro Hospitalar do Porto · PTPolytechnic Institute of Viana do Castelo · PTUniversidade Católica Portuguesa · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work aimed to evaluate how aging could influence patients' perception of health quality of life (HRQOL), as well as, the effect of aging on dialysis adequacy and in hematological, iron status, inflammatory and nutritional markers. In this transversal study were enrolled 305 ESRD patients under online-hemodiafiltration (OL-HDF) (59.67% males; 64.9 ± 14.3 years old). Data about comorbidities, hematological data, iron status, dialysis adequacy, nutritional and inflammatory markers were collected from patient's records. Moreover, HRQOL score, by using the Kidney Disease Quality of Life-Short Form (KDQOL-SF), was assessed. Analyzing the results according to quartiles of age, significant differences were found for some parameters evaluated by the KDQOL-SF instrument, namely for work status, physical functioning and role-physical, which decreased with increasing age. We also found a higher proportion of diabetic patients, a decrease in creatinine, iron, albumin serum levels, transferrin saturation and nPCR, with increasing age. Moreover, significant negative correlations were found between age and mean cell hemoglobin concentration, iron, transferrin saturation, albumin, nPCR, work status, physical functioning and role-physical. In conclusion, our results showed that aging is associated with a decreased work status, physical functioning and role-physical, with a decreased dialysis adequacy, iron availability and nutritional status, and with an increased proportion of diabetic patients and of patients using central venous catheter, as the vascular access. The knowledge of these changes associated with aging, which have impact in the quality of life of the patients, could be useful in their management.

Indexed as

agingdialysis adequacygenderHealth-related quality of lifeiron availabilitynutritional statuson-line hemodiafiltration

Identifiers

PMID25657849
PMCPMC4306470
OpenAlexW2015844518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.