Evidence map›Paper›PMID 25657827›Full record

ArticleJournal of biomedical science and engineering2014

The P2Y

Zhongji Liao, Chen Cao, Jianjie Wang, Virginia H Huxley, Olga Baker, Gary A Weisman, Laurie Erb

Open access · diamondAbstract read
In one paragraph

Article in Journal of biomedical science and engineering, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Role of the Purinergic P2Y2 Receptor in Pulmonary Hypertension.International journal of environmental research and public health · 2021
    Review
  3. Review
  4. Article
  5. Purinergic P2YCellular and molecular life sciences : CMLS · 2020
    Article
  6. Upregulation of P2YFrontiers in cellular and infection microbiology · 2018
    Article
  7. P2YCellular and molecular life sciences : CMLS · 2017
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Zhongji LiaoDepartment of Medicine, University of California, San Diego, USA.
Chen CaoDepartment of Biochemistry, Life Sciences Center, University of Missouri, Columbia, USA.
Jianjie WangDepartment of Biomedical Sciences, Missouri State University, Springfield, USA.
Virginia H HuxleyDepartment of Medical Pharmacology and Physiology, University of Missouri, Columbia, USA.
Olga BakerSchool of Dentistry, University of Utah, Salt Lake City, USA.
Gary A WeismanDepartment of Biochemistry, Life Sciences Center, University of Missouri, Columbia, USA.
Laurie ErbDepartment of Biochemistry, Life Sciences Center, University of Missouri, Columbia, USA.
University of Missouri · USMissouri State University · USUniversity of California San Diego · USUniversity of Utah · US

Funding

PATHOGENESIS OF PHOSPHOLIPASES A2 IN ADP01AG018357 · NIA · UNIVERSITY OF MISSOURI-COLUMBIA · PI SUN, GRACE Y · 2001 to 2012
$10.4M
VIP RECEPTORS AND SUBMANDIBULAR GLAND FUNCTIONR01DE007389 · NIDCR · UNIVERSITY OF MISSOURI-COLUMBIA · PI WEISMAN, GARY ANDREW · 1988 to 2020
$7.6M
Restoring Salivary Gland Function by Reducing Nucleotide-induced InflammationR01DE023342 · NIDCR · UNIVERSITY OF MISSOURI-COLUMBIA · PI WEISMAN, GARY ANDREW · 2014 to 2018
$2.9M
Investigating the role of the P2Y2 nucleotide receptor in inflammationR21HL088228 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI ERB, LAURIE · 2007 to 2009
$511k
NHLBI NIH HHS R21 HL088228NIA NIH HHS P01 AG018357NIDCR NIH HHS R01 DE007389NIDCR NIH HHS R01 DE023342
6 · The paper itself

Abstract

Vascular endothelial cadherin (VE-cadherin) mediates homophylic adhesion between endothelial cells and is an important regulator of angiogenesis, blood vessel permeability and leukocyte trafficking. Rac1, a member of the Rho family of GTPases, controls VE-cadherin adhesion by acting downstream of several growth factors, including angiopoietin-1 and vascular endothelial growth factor (VEGF). Here we show that UTP-induced activation of the G

Indexed as

Adherens JunctionsEndotheliumP2Y ReceptorsRacVE-Cadherin

Identifiers

PMID25657827
PMCPMC4314728
OpenAlexW1982541838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.