ArticleFrontiers in microbiology2015
Methanothermobacter thermautotrophicus modulates its membrane lipids in response to hydrogen and nutrient availability.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 39 citations in OpenAlex.
- A high-pressure bioreactor system for the cultivation of Methanothermobacter marburgensis on advanced growth media for sustainable energy applications.Scientific reports · 2025Article
- Photosynthesis: Genetic Strategies Adopted to Gain Higher Efficiency.International journal of molecular sciences · 2024Review
- Unraveling the multiplicity of geranylgeranyl reductases in Archaea: potential roles in saturation of terpenoids.Extremophiles : life under extreme conditions · 2024Review
- The Targeted Deletion of Genes Responsible for Expression of the Mth60 Fimbriae Leads to Loss of Cell-Cell Connections in Methanothermobacter thermautotrophicus ΔH.Applied and environmental microbiology · 2023Article
- Intact polar lipidome and membrane adaptations of microbial communities inhabiting serpentinite-hosted fluids.Frontiers in microbiology · 2023Article
- The Exploration of theFrontiers in microbiology · 2022Article
- Certain, but Not All, Tetraether Lipids from the Thermoacidophilic ArchaeonInternational journal of molecular sciences · 2021Article
- Enhanced methane production from cellulose using a two-stage process involving a bioelectrochemical system and a fixed film reactor.Biotechnology for biofuels · 2021Article
- Structural studies of geranylgeranylglyceryl phosphate synthase, a prenyltransferase found in thermophilic Euryarchaeota.Acta crystallographica. Section D, Structural biology · 2020Article
- Novel Intact Polar and Core Lipid Compositions in theBiomolecules · 2020Article
- The influence of the specific growth rate on the lipid composition of Sulfolobus acidocaldarius.Extremophiles : life under extreme conditions · 2020Article
- Membrane Lipid Composition and Amino Acid Excretion Patterns ofLife (Basel, Switzerland) · 2019Article
- Membrane Lipid Composition of the Moderately Thermophilic Ammonia-Oxidizing Archaeon "Applied and environmental microbiology · 2019Article
- In Search for the Membrane Regulators of Archaea.International journal of molecular sciences · 2019Review
- Heat Stress Dictates Microbial Lipid Composition along a Thermal Gradient in Marine Sediments.Frontiers in microbiology · 2017Article
- Unusual Butane- and Pentanetriol-Based Tetraether Lipids in Methanomassiliicoccus luminyensis, a Representative of the Seventh Order of Methanogens.Applied and environmental microbiology · 2016Article
- Influence of Growth Phase, pH, and Temperature on the Abundance and Composition of Tetraether Lipids in the Thermoacidophile Picrophilus torridus.Frontiers in microbiology · 2016Article
- The Effects of Temperature and Growth Phase on the Lipidomes of Sulfolobus islandicus and Sulfolobus tokodaii.Life (Basel, Switzerland) · 2015Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Methanothermobacter thermautotrophicus strain ΔH is a model hydrogenotrophic methanogen, for which extensive biochemical information, including the complete genome sequence, is available. Nevertheless, at the cell membrane lipid level, little is known about the responses of this archaeon to environmental stimuli. In this study, the lipid composition of M. thermautotrophicus was characterized to verify how this archaeon modulates its cell membrane components during growth phases and in response to hydrogen depletion and nutrient limitation (potassium and phosphate). As opposed to the higher abundance of phospholipids in the stationary phase of control experiments, cell membranes under nutrient, and energy stress were dominated by glycolipids that likely provided a more effective barrier against ion leakage. We also identified particular lipid regulatory mechanisms in M. thermautotrophicus, which included the accumulation of polyprenols under hydrogen-limited conditions and an increased content of sodiated adducts of lipids in nutrient-limited cells. These findings suggest that M. thermautotrophicus intensely modulates its cell membrane lipid composition to cope with energy and nutrient availability in dynamic environments.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.