ReviewFrontiers in microbiology2014
Roles of thermostable direct hemolysin (TDH) and TDH-related hemolysin (TRH) in Vibrio parahaemolyticus.
Review in Frontiers in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers.
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Who cites it
127 citing papers in PubMed, 262 citations in OpenAlex.
- Apparent expansion of virulentVirulence · 2026Article
- Transcriptomic dissection of the ToxR regulon in Vibrio parahaemolyticus at low cell density.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Protective effect of Glutamicibacter sp. ZY1 against Vibrio parahaemolyticus YDE17 pathogenicity in the clam Ruditapes philippinarum.World journal of microbiology & biotechnology · 2026Article
- Examining pathogenicApplied and environmental microbiology · 2026Article
- Microbiological safety and hygiene monitoring of coastal seawater at Northern public beaches of Mauritius and genetic characterization of human pathogenic Vibrio species.PLOS global public health · 2026Article
- Population structure and phylogenetic analysis of Vibrio cholerae non-O1/O139 by whole genome sequencing.PloS one · 2026Article
- Proteomic adaptation of the hypervirulent pandemicFrontiers in microbiology · 2026Article
- Interpretable learning algorithms enable pathogenic potential assessment and virulence-associated gene discovery ofFrontiers in microbiology · 2026Article
- Beyond AMR and virulence databases: genome wide associations of closely relatedFrontiers in microbiology · 2026Article
- Article
- Genomic and resistome characterization of a multidrug-resistantFrontiers in microbiology · 2026Article
- Metagenomic analysis and proteins prediction of emerging pathogens in artisanal cheese.Molecular diversity · 2025Article
- Sodium taurocholate induces a colonization-adapted state in Vibrio parahaemolyticus by repressing acute virulence and promoting adhesion.BMC microbiology · 2025Article
- Water Parameters Predicting the Seasonal and Spatial Dynamics of the Vibrio Harveyi- and Splendidus-Clade Pathogens.Microorganisms · 2025Article
- Unveiling pathogenicity and resistance profiles of non-cholera Vibrio from an urban estuary.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- The Toxin GeneMicroorganisms · 2025Article
- Prevalence and Genomic Characterization ofFoods (Basel, Switzerland) · 2025Article
- Long-term analysis of Vibrio vulnificus and Vibrio parahaemolyticus virulence factors and their environmental associations in the Chesapeake Bay, Maryland, US.Journal of applied microbiology · 2025Article
- Draft genomes of twoMicrobiology resource announcements · 2025Article
- A One Health Insight into NoncholericOpen forum infectious diseases · 2025Article
67 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vibrio parahaemolyticus is the leading cause of seafood borne bacterial gastroenteritis in the world, often associated with the consumption of raw or undercooked seafood. However, not all strains of V. parahaemolyticus are pathogenic. The thermostable direct hemolysin (TDH) or TDH-related hemolysin (TRH) encoded by tdh and trh genes, respectively, are considered major virulence factors in V. parahaemolyticus. However, about 10% of clinical strains do not contain tdh and/or trh. Environmental isolates of V. parahaemolyticus lacking tdh and/or trh are also highly cytotoxic to human gastrointestinal cells. Even in the absence of these hemolysins, V. parahaemolyticus remains pathogenic indicating other virulence factors exist. This mini review aims at discussing the possible roles of tdh and trh genes in clinical and environmental isolates of V. parahaemolyticus.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.