Evidence map›Paper›PMID 25657541›Full record

ArticleUrology annals

Prostate laser vaporization is safe and effective in elderly men.

Rohit Majumdar, Hossein S Mirheydar, Kerrin L Palazzi, Charles M Lakin, Michael E Albo, J Kellogg Parsons

Open access · goldAbstract read
In one paragraph

Article in Urology annals. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rohit MajumdarUniversity of California, San Diego School of Medicine, La Jolla, USA.
Hossein S MirheydarUniversity of California, San Diego School of Medicine, La Jolla, USA ; Department of Urology, UC San Diego Health System, San Diego, USA.
Kerrin L PalazziUrologic Cancer, UC San Diego Moores Cancer Center, La Jolla, USA.
Charles M LakinUniversity of California, San Diego School of Medicine, La Jolla, USA ; Department of Urology, UC San Diego Health System, San Diego, USA.
Michael E AlboUniversity of California, San Diego School of Medicine, La Jolla, USA ; Department of Urology, UC San Diego Health System, San Diego, USA.
J Kellogg ParsonsUniversity of California, San Diego School of Medicine, La Jolla, USA ; Department of Urology, UC San Diego Health System, San Diego, USA ; Urologic Cancer, UC San Diego Moores Cancer Center, La Jolla, USA ; Section of Urology, VA San Diego Healthcare System, San Diego, CA, USA.
University of California, San Diego · USUC San Diego Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere are few data on the safety and efficacy of laser photoselective vaporization (LVP) in elderly men. We compared the safety and efficacy of LVP for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men ≥75 years, who we defined as elderly, to those <75 years. MATERIALS AND

methodsSafety and efficacy outcomes in elderly men undergoing LVP for lower urinary tract symptoms secondary to BPH from 2005 to 2012 were compared with men <75 years. Differences between-groups in demographics, perioperative outcomes, complications, and postoperative changes in International Prostate Symptom Score (I-PSS) were calculated.

resultsOf 202 patients, 49 (24%) were elderly (range: 75-95 years) and 153 (76%) were <75 years. Preoperatively, elderly men were more likely to have heart disease (35% vs. 20%, P = 0.03), gross hematuria (6.1% vs. 0.7%, P = 0.05), urinary retention (57% vs. 41%, P = 0.07), and take anti-coagulants (61% vs. 35%, P = 0.002). Elderly men had a longer median length of stay (1 day vs. 0 day, P = 0.001). There were no significant between-group differences in transfusion frequency (4.4% vs. 0.7%, P = 0.14) or Clavien III complications (2% vs. 2.6%, P = 1.0). One month postsurgery, elderly patients reported smaller median decreases in I-PSS (5.5 vs. 9, P = 0.02) and urinary bother (1 point vs. 2, P = 0.03) compared with preoperative values. At till 9 months follow-up, there were no significant between-group differences in median I-PSS or urinary bother scores.

conclusionsDespite a higher prevalence of preoperative comorbidity and urinary retention, elderly LVP patients experienced perioperative safety and shorter term efficacy outcomes comparable to younger men.

Indexed as

Benign prostatic hyperplasiacomplicationselderlylower urinary tract symptomsoutcomes

Identifiers

PMID25657541
PMCPMC4310114
OpenAlexW1973433908

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.