ArticleIndian journal of dermatology
How Effective is Autologous Serum Therapy in Chronic Autoimmune Urticaria.
Article in Indian journal of dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- Current and Emerging Therapies for Chronic Spontaneous Urticaria: A Narrative Review.Dermatology and therapy · 2023Review
- Autologous serum therapy reduces the symptoms and antihistamine burden in patients with chronic urticaria.Postepy dermatologii i alergologii · 2023Article
- Weekly injection of histaglobulin produces long-term remission in chronic urticaria: A prospective clinical study.Indian journal of pharmacologyArticle
- Consensus Statement for the Diagnosis and Treatment of Urticaria: A 2017 Update.Indian journal of dermatologyReview
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic autoimmune urticaria (CAU) is one of the most challenging therapeutic problems faced by a dermatologist. Recently, weekly autologous serum injections have been shown to induce a prolonged remission in this disease.
aimTo evaluate the efficacy of repeated autologous serum injections in patients with CAU. MATERIALS AND
methodsSeventy patients of CAU were prospectively analyzed for the efficacy of nine consecutive weekly autologous serum injections with a post-intervention follow-up of 12 weeks. Total urticaria severity score (TSS) was monitored at the baseline, at the end of treatment and lastly at the end of 12 weeks of follow up. Response to treatment was judged by the percentage reduction in baseline TSS at the end of treatment and again at the end of 12 weeks-follow-up.
resultsOut of the 70 patients enrolled, 11 dropped out of the injection treatment after one or the first few doses only. Among the rest of 59 patients, only 7 patients (12%) went into a partial or complete remission and remained so over the follow-up period of 12 weeks. Forty patients (68%) did not demonstrate any significant reduction in TSS at the end of the treatment period. Rest of the 12 patients showed either a good or excellent response while on weekly injection treatment, but all of them relapsed over the follow-up period of 12 weeks.
conclusionAutologous serum therapy does not seem to lead to any prolonged remission in patients of CAU.
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