Evidence map›Paper›PMID 25656921›Full record

ArticleAnnals of epidemiology2015

Risk factors for pancreatitis in older women: the Iowa Women's Health Study.

Anna E Prizment, Eric H Jensen, Anne M Hopper, Beth A Virnig, Kristin E Anderson

Registry-linked trialAbstract read
In one paragraph

Article in Annals of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04761523 (The Effect of Dietary Fat Content on the Recurrence of Pancreatitis), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04761523 narecruitingnot on this mapstarted 2022, after this paper: background citation

The Effect of Dietary Fat Content on the Recurrence of Pancreatitis (EFFORT): Protocol of a Multicentre Randomized Controlled Trial

TypeinterventionalSponsorUniversity of PecsRan2022 to 2026Enrolled384ConditionsAcute PancreatitisArmsDietary intervention: reduced fat diet, Dietary intervention: standard healthy diet
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  4. Review
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  10. Dietary Factors Reduce Risk of Acute Pancreatitis in a Large Multiethnic Cohort.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anna E PrizmentDivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis; Masonic Cancer Center, University of Minnesota, Minneapolis. Electronic address: prizm001@umn.edu.
Eric H JensenDivision of Surgical Oncology, University of Minnesota Medical School, Minneapolis.
Anne M HopperMasonic Cancer Center, University of Minnesota, Minneapolis.
Beth A VirnigDivision of Health Policy and Management, School of Public Health, Masonic Cancer Center, University of Minnesota, Minneapolis.
Kristin E AndersonDivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis; Masonic Cancer Center, University of Minnesota, Minneapolis.
University of Minnesota · USUniversity of Minnesota Medical Center · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
EPIDEMIOLOGY OF CANCER IN A COHORT OF OLDER WOMENR01CA039742 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI LAZOVICH, DEANN · 1985 to 2014
$8.0M
NCATS NIH HHS UL1 TR000114NCATS NIH HHS UL1TR000114NCI NIH HHS R01 CA039742NCI NIH HHS R01CA039742
6 · The paper itself

Abstract

purposePancreatitis-an inflammation of pancreas-is a severe and costly disease. Although many risk factors for pancreatitis are known, many pancreatitis cases, especially in elderly women, are of unknown etiology.

methodsRisk factors for acute pancreatitis (AP) and chronic pancreatitis (CP) were assessed in a prospective cohort (n = 36,436 women, aged ≥ 65 years). Exposures were self-reported at baseline. Pancreatitis was ascertained by linkage to Medicare claims (1986-2004) categorized by a physician as follows: "AP", one AP episode (n = 511) or "CP", 2+ AP or 1+ CP episodes (n = 149).

resultsMultivariable odds ratios (ORs) and 95% confidence intervals for AP and CP were calculated using multinomial logistic regression. Alcohol use was not associated with AP or CP. Heavy smoking (40+ vs. 0 pack-years) was associated with a twofold increased OR for CP. For body mass index greater than or equal to 30 versus less than 25 kg/m(2), the ORs were 1.35 (1.07-1.70) for AP (P trend = .009) and 0.59 (0.37-0.94) for CP (P trend = .01). ORs for AP and CP were increased for hormone replacement therapy use, heart disease, and hypertension. There were positive significant associations between protein and total fat intake for CP and AP.

conclusionsWe identified factors associated with AP and CP that may be specific to older women.

Indexed as

Acute DiseaseAgedAlcohol DrinkingBody Mass IndexCardiovascular DiseasesDietEstrogen Replacement TherapyFemaleHumansIowaMedicarePancreatitisPancreatitis, ChronicProspective StudiesRisk FactorsSmokingCohortElderlyMedicarePancreatitis

Identifiers

PMID25656921
PMCPMC4457556
OpenAlexW2166209010

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.