Evidence map›Paper›PMID 25655765›Full record

ArticleInternational journal of oral and maxillofacial surgery2015

Postoperative nausea and vomiting following orthognathic surgery.

C Phillips, C D Brookes, J Rich, J Arbon, T A Turvey

2 registry-linked trialsAbstract read
In one paragraph

Article in International journal of oral and maxillofacial surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 4 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04112771 completednot on this mapstarted 2019, after this paper: background citation

Effects of Penehyclidine on Postoperative Nausea and Vomiting in Patients Underging Bimaxillary Surgery: A Retrospective Cohort Study

TypeobservationalSponsorPeking University First HospitalRan2019 to 2019Enrolled243ConditionsPenehyclidine, Postoperative Nausea and Vomiting, Bimaxillar SurgeryArmsPenehyclidine hydrochloride, No penehyclidine hydrochloride
NCT04454866 nacompletednot on this mapstarted 2020, after this paper: background citation

Effects of Penehyclidine in Preventing Postoperative Nausea and Vomiting in Patients Underging Bimaxillary Surgery: A Randomised Controlled Trial

TypeinterventionalSponsorPeking University First HospitalRan2020 to 2021Enrolled354ConditionsPenehyclidine, Postoperative Nausea and Vomiting, Bimaxillar SurgeryArmsSingle injection of penehyclidine, Continuous infusion of penehyclidine, Placebo
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 4 syntheses or guidelines pooled it, 98 citations in OpenAlex.

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  11. Postdischarge Nausea and Vomiting Remains Frequent After Le Fort I Osteotomy Despite Implementation of a Multimodal Antiemetic Protocol Effective in Reducing Postoperative Nausea and Vomiting.Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2015
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  18. [Causes and prevention strategies of postoperative nausea and vomiting after orthognathic surgery].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025
    Review
  19. Evaluation of the Relationship Between Preoperative Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio and Postoperative Nausea and Vomiting in Rhinoplasty Surgery.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

C PhillipsDepartment of Orthodontics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: Ceib_Phillips@unc.edu.
C D BrookesDepartment of Oral and Maxillofacial Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
J RichDepartment of Orthodontics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
J ArbonPrivate Practice, Cary, NC, USA.
T A TurveyDepartment of Oral and Maxillofacial Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USBennett Aerospace (United States) · US

Funding

INFLUENCES ON STABILITY FOLLOWING ORTHOGNATHIC SURGERYR01DE005215 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PHILLIPS, CEIB · 1985 to 2013
$6.3M
NIDCR NIH HHS R01 DE005215NIDCR NIH HHS R01DE005215
6 · The paper itself

Abstract

The purpose of this study was to assess the incidence and risk factors associated with postoperative nausea (PON) and vomiting (POV) after orthognathic surgery. A review of the clinical records of consecutively enrolled subjects (2008-2012) at a single academic institution was conducted between 9/2013 and 3/2014. Data on the occurrence of PON and POV and potential patient-related, intraoperative, and postoperative explanatory factors were extracted from the medical records. Logistic models were used for the presence/absence of postoperative nausea and vomiting separately. Data from 204 subjects were analyzed: 63% were female, 72% Caucasian, and the median age was 19 years. Thirty-three percent had a mandibular osteotomy alone, 27% a maxillary osteotomy alone, and 40% had bimaxillary osteotomies. Sixty-seven percent experienced PON and 27% experienced POV. The most important risk factors for PON in this series were female gender, increased intravenous fluids, and the use of nitrous oxide, and for POV were race, additional procedures, and morphine administration. The incidence of PON and POV following orthognathic surgery in the current cohort of patients, after the introduction of the updated 2007 consensus guidelines for the management of postoperative nausea and vomiting, has not decreased substantially from that reported in 2003-2004.

Indexed as

Orthognathic SurgeryAdolescentAdultFemaleHumansIncidenceMaleMiddle AgedNorth CarolinaPostoperative Nausea and VomitingRisk Factorsorthognathic surgerypostoperative nauseapostoperative vomiting

Identifiers

PMID25655765
PMCPMC4430405
OpenAlexW2032889728

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.