Evidence map›Paper›PMID 25655672›Full record

ArticleScientific reports2015

Shorter spontaneous fixation durations in infants with later emerging autism.

Sam V Wass, Emily J H Jones, Teodora Gliga, Tim J Smith, Tony Charman, Mark H Johnson, BASIS team

Abstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
  4. Trial
  5. Visual function and autism spectrum disorder.Journal of neural transmission (Vienna, Austria : 1996) · 2026
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  20. Cytokine Dynamics in Autism: Analysis of BMAC Therapy Outcomes.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Sam V WassMedical Research Council Cognition and Brain Sciences Unit, Cambridge, UK.
Emily J H JonesCentre for Brain and Cognitive Development, Birkbeck, University of London, UK.
Teodora GligaCentre for Brain and Cognitive Development, Birkbeck, University of London, UK.
Tim J SmithCentre for Brain and Cognitive Development, Birkbeck, University of London, UK.
Tony CharmanKing's College London, Institute of Psychiatry, Psychology &Neuroscience, Department of Psychology, UK.
Mark H JohnsonCentre for Brain and Cognitive Development, Birkbeck, University of London, UK.
BASIS team

Funding

Medical Research Council G0701484Medical Research Council MC_UP_A060_1104Medical Research Council MR/K021389/1
6 · The paper itself

Abstract

Little is known about how spontaneous attentional deployment differs on a millisecond-level scale in the early development of autism spectrum disorders (ASD). We measured fine-grained eye movement patterns in 6-to 9-month-old infants at high or low familial risk (HR/LR) of ASD while they viewed static images. We observed shorter fixation durations (i.e. the time interval between saccades) in HR than LR infants. Preliminary analyses indicate that these results were replicated in a second cohort of infants. Fixation durations were shortest in those infants who went on to receive an ASD diagnosis at 36 months. While these findings demonstrate early-developing atypicality in fine-grained measures of attentional deployment early in the etiology of ASD, the specificity of these effects to ASD remains to be determined.

Indexed as

Eye MovementsAutism Spectrum DisorderFemaleHumansInfantMaleTime Factors

Identifiers

PMID25655672
PMCPMC4319149

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.