ArticleAmerican journal of speech-language pathology2015
Primary progressive apraxia of speech: clinical features and acoustic and neurologic correlates.
Article in American journal of speech-language pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06181500 (Home-Based Exercise in Primary Progressive Aphasia), which is not on this map. Cited by 50 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Home-Based Exercise in Primary Progressive Aphasia: A Pilot Study
Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.
- Behavioral Treatment for Speech and Language in Primary Progressive Aphasia and Primary Progressive Apraxia of Speech: A Systematic Review.Neuropsychology review · 2024Pooled it
- Trial
- Deep learning-derived measures of sound-level accuracy in primary progressive apraxia of speech: A feasibility pipeline with descriptive evidence from two cases.Clinical linguistics & phonetics · 2026Article
- Evaluating Goodness of Pronunciation and Phonological Posteriors as Objective Markers of Speech Severity in Motor Speech Disorders.medRxiv : the preprint server for health sciences · 2026Article
- Written picture descriptions distinguish variants of primary progressive aphasia.Journal of Alzheimer's disease : JAD · 2025Article
- Primary Progressive Aphasia Treatment: Current Treatment Options in Neurology Article Topic: Management of Primary Progressive Aphasia.Current treatment options in neurology · 2025Review
- Automatic Speech Recognition in Primary Progressive Apraxia of Speech.Journal of speech, language, and hearing research : JSLHR · 2024Article
- Identifying and Addressing Functional Communication Challenges in Patients With Behavioral Variant Frontotemporal Dementia.American journal of speech-language pathology · 2024Article
- Connected Speech Fluency in Poststroke and Progressive Aphasia: A Scoping Review of Quantitative Approaches and Features.American journal of speech-language pathology · 2024Article
- Efficacy of LSVT LOUDBrain sciences · 2024Article
- Characterizing Speech Errors Across Primary Progressive Apraxia of Speech Subtypes.Journal of speech, language, and hearing research : JSLHR · 2024Article
- Diffusion tensor imaging-based multi-fiber tracking reconstructions can regionally differentiate phonetic versus prosodic subtypes of progressive apraxia of speech.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Normative Values for Word Syllable Duration With Interpretation in a Large Sample of Stroke Survivors With Aphasia.American journal of speech-language pathology · 2023Article
- Longitudinal characterization of patients with progressive apraxia of speech without clearly predominant phonetic or prosodic speech features.Brain and language · 2023Article
- Rate Modulation Abilities in Acquired Motor Speech Disorders.Journal of speech, language, and hearing research : JSLHR · 2023Article
- An Update on Apraxia of Speech.Current neurology and neuroscience reports · 2023Review
- Acoustic Analysis and Neuroimaging Correlates of Diadochokinetic Rates in Mild-Moderate Primary Progressive Apraxia of Speech.Brain and language · 2023Article
- Clinicopathological associations of hemispheric dominance in primary progressive apraxia of speech.European journal of neurology · 2023Article
- The Apraxia of Speech Rating Scale: Reliability, Validity, and Utility.American journal of speech-language pathology · 2023Article
- Apraxia of Speech in the Spontaneous Speech of Nonfluent/Agrammatic Primary Progressive Aphasia.Journal of Alzheimer's disease reports · 2023Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
purposeThis study summarizes 2 illustrative cases of a neurodegenerative speech disorder, primary progressive apraxia of speech (AOS), as a vehicle for providing an overview of the disorder and an approach to describing and quantifying its perceptual features and some of its temporal acoustic attributes.
methodTwo individuals with primary progressive AOS underwent speech-language and neurologic evaluations on 2 occasions, ranging from 2.0 to 7.5 years postonset. Performance on several tests, tasks, and rating scales, as well as several acoustic measures, were compared over time within and between cases. Acoustic measures were compared with performance of control speakers.
resultsBoth patients initially presented with AOS as the only or predominant sign of disease and without aphasia or dysarthria. The presenting features and temporal progression were captured in an AOS Rating Scale, an Articulation Error Score, and temporal acoustic measures of utterance duration, syllable rates per second, rates of speechlike alternating motion and sequential motion, and a pairwise variability index measure.
conclusionsAOS can be the predominant manifestation of neurodegenerative disease. Clinical ratings of its attributes and acoustic measures of some of its temporal characteristics can support its diagnosis and help quantify its salient characteristics and progression over time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.