Evidence map›Paper›PMID 25654035›Full record

ArticleJournal of clinical and diagnostic research : JCDR2014

Novel therapeutic approach for the treatment of periodontitis by curcumin.

Madhu Bhatia, Shilpa Sarvesh Urolagin, Kishore Babu Pentyala, Sarvesh Basavaraj Urolagin, Menaka K B, Shreedevi Bhoi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 6 pooled it
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 6 syntheses or guidelines pooled it, 93 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Clinical Effectiveness of Herbal Oral Care Products in Periodontitis Patients: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Curcumin inhibits growth ofJournal of oral microbiology · 2024
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Madhu BhatiaPrivate Practioner, Department of Periodontics, New you Cosmetic Clinic , Bangalore, Karnataka, India .
Shilpa Sarvesh UrolaginLecturer, Department of Periodontics, Narsinhbhai Patel Dental College , North Gujarat, India.
Kishore Babu PentyalaPrivate Practioner, Department of Oral & Maxillofacial Surgery, New you Cosmetic Clinic , Bangalore, Karnataka, India .
Sarvesh Basavaraj UrolaginReader, Department of Oral & Maxillofacial Surgery, Narsinhbhai Patel Dental College , North Gujarat, India .
Menaka K BReader, Department of Periodontics, KLE V. K. Institute of Dental Sciences , Belgaum, Karnataka, India .
Shreedevi BhoiLecturer, Department of Oral & Maxillofacial Surgery, Narsinhbhai Patel Dental College , North Gujarat, India .
Cosmetics Europe · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS AND

objectivesThe aim of the present study was to evaluate the clinical and microbiological efficacy of locally delivered 1% curcumin gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis. MATERIALS AND

methodsThe study group consisted of 25 patients, belonging to both sex, aged between 21-45 years. All patients diagnosed as chronic periodontitis with periodontal pockets of depth >5mm bilaterally were randomly selected. A split mouth design was followed and the patients received a complete prophylaxis including scaling and root planing. Examination of plaque index, bleeding index, probing pocket depth and clinical attachment level were measured for each patient. The test group received 1% curcumin gel along with scaling and root planing whereas the control group received scaling and root planing alone followed by microbiological samples taken at baseline, 1, 3 and 6 months interval.

resultsThe 1% curcumin gel appeared to provide significant improvements in clinical parameters. Microbiological counts of Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum and capnocytophaga showed significant reduction in periopathogens at the test sites after six months when compared with that of control sites.

conclusionLocally delivered 1% curcumin gel was more effective in inhibiting the growth of oral bacteria when used as an adjunct to SRP in the treatment of chronic periodontitis.

Indexed as

CurcuminLocal drug deliveryPeriodontitis

Identifiers

PMID25654035
PMCPMC4316341
OpenAlexW2130175884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.