Evidence map›Paper›PMID 25653995›Full record

ArticleJournal of clinical and diagnostic research : JCDR2014

Arnold Chiari malformation with spina bifida: a lost opportunity of folic Acid supplementation.

Deepa Ganesh, Benjamin M Sagayaraj, Ravi Kumar Barua, Nidhi Sharma, Upasana Ranga

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Deepa GaneshAssistant Professor, Department of Gynaecology, Saveetha Medical College and Hospital , Chennai, Tamilnadu, India .
Benjamin M SagayarajAssociate Professor, Department of Paediatrics, Saveetha Medical College and Hospital , Chennai, Tamilnadu, India .
Ravi Kumar BaruaProfessor, Department of Gynaecology, Saveetha Medical College and Hospital , Chennai, Tamilnadu, India .
Nidhi SharmaAssociate Professor, Department of Gynaecology, Saveetha Medical College and Hospital , Chennai, Tamilnadu, India .
Upasana RangaAssociate Professor, Department of Radiology, Saveetha Medical College and Hospital , Chennai, Tamilnadu, India .
Saveetha University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Arnold Chiari (kee-AHR-ee) II malformation elongated cerebellar tonsils are displaced inferiorly through the Foramen Magnum into the upper cervical spinal canal. It is a complex anomaly with skull, dura, brain, spine and cord manifestations. Meningomyelocele is seen in all cases. We present a case of type II Arnold Chiari Malformation diagnosed in utero in a pregnant lady .There was no periconceptional folic acid supplementation. As the role of the Methylene Tetra Hydro Folate Reductase gene polymorphism in neural tube defects is becoming evident, a simple opportunity as folic acid supplementation should not be missed. Folate supplementation as fortification of cereal grains will also prevent other conditions like congenital heart defects, urinary tract anomalies, orofacial defects, limb defects and pyloric stenosis.

Indexed as

Arnold chiariFolic acidPericonceptionPregnancy

Identifiers

PMID25653995
PMCPMC4316301
OpenAlexW2092724023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.