Evidence map›Paper›PMID 25653943›Full record

ArticleJournal of clinical and diagnostic research : JCDR2014

Identifying Candida and other yeast-like fungi: utility of an identification algorithm in resource limited setting.

Vidya Nerurkar, Suveb Khan, Sushma Kattungal, Simi Bhatia

Abstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vidya NerurkarSection Head-Microbiology, EIA & Serology, SRL Ltd. , Mumbai, India .
Suveb KhanSenior Scientific Officer, SRL Ltd , Mumbai, India .
Sushma KattungalSection Technical Manager, SRL Ltd . Mumbai, India .
Simi BhatiaLaboratory Director, SRL Ltd . Mumbai, India .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe increasing recovery rates of unusual yeasts with innate drug resistance make accurate identification crucial for successful therapy and infection control measures. The current study was undertaken to study the utility of CHROMagar Candida (CC) and evaluate an identification algorithm, using germ tube test (GT), CC and a commercial identification kit, API ID 32C. SETTINGS AND

designThe prospective study was carried out at a private laboratory in Mumbai, India. MATERIALS AND

methodsIdentification of 533 yeast and yeast like isolates was carried out using an identification algorithm, comprising of the GT, CC and API tests.

resultsCC was useful to detect mixed cultures. We were able to identify 393/533, i.e. 73.7 % of isolates using GT and CC Tests only. This was because C. albicans and C. tropicalis, which can be reliably identified using CC, constituted 75.2 % of the isolates. We were unable to identify 140 isolates, i.e. 26.3 %, using GT and CC tests only and performed additional testing using API ID 32C. CC was not found to be reliable in identifying C. krusei.

conclusionThe diverse identification profile obtained in our study substantiates the need for all diagnostic microbiology laboratories to be better prepared for identifying unusual yeasts. Though GT or CC testing cannot alone suffice for identification of all clinically encountered Candida and yeast-like fungi, use of GT, CC and automated identification systems in a step-wise algorithm can enable the same in a more cost effective manner.

Indexed as

AlgorithmCandidaCHROMagarTMCandidaID32CYeast

Identifiers

PMID25653943
PMCPMC4316249

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.