Evidence map›Paper›PMID 25653870›Full record

ArticleJournal of ophthalmology2015

A Comparison of Clinical Features between Community-Associated and Healthcare-Associated Methicillin-Resistant Staphylococcus aureus Keratitis.

Ching-Hsi Hsiao, Sherine Jue Ong, Chih-Chun Chuang, David H K Ma, Yhu-Chering Huang

Abstract read
In one paragraph

Article in Journal of ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. International journal of molecular sciences · 2022
    Article
  3. Article
  4. Comparison of Methicillin-ResistantJournal of clinical medicine · 2019
    Article
  5. Article
  6. Detection of methicillin-resistantIranian journal of microbiology · 2018
    Article
  7. Review
  8. Ex vivo rabbit and human corneas as models for bacterial and fungal keratitis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ching-Hsi HsiaoDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou 33305, Taiwan ; College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0001-5745-9371
Sherine Jue OngDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou 33305, Taiwan ; Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung 20448, Taiwan.
Chih-Chun ChuangDepartment of Ophthalmology, Changhua Christian Hospital, Changhua 50006, Taiwan.
David H K MaDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou 33305, Taiwan ; College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Yhu-Chering HuangCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan ; Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose. To compare the clinical features of community-associated (CA) and healthcare-associated (HA) methicillin-resistant Staphylococcus aureus (MRSA) keratitis. Methods. Patients presenting with culture-proven MRSA keratitis between January 1, 2006, and December 31, 2010, at Chang Gung Memorial Hospital, Taiwan, were included in this study. The patients' demographic and clinical information were reviewed retrospectively. Antibiotic susceptibility was verified using the disk diffusion method. Results. Information on 26 patients with MRSA keratitis was collected, including 12 cases of CA-MRSA and 14 cases of HA-MRSA. All MRSA isolates were susceptible to vancomycin; the only difference in drug susceptibility was that CA-MRSA isolates were more susceptible to trimethoprim/sulfamethoxazole than HA-MRSA (P = .034). The most common risk factor for MRSA keratitis was ocular surface disease. No significant differences were observed between the 2 groups in terms of clinical features, treatments, and visual outcomes. Conclusion. In Taiwan, CA-MRSA rivals HA-MRSA as a critical cause of MRSA keratitis. Furthermore, CA-MRSA isolates are multidrug resistant. CA-MRSA and HA-MRSA keratitis are clinically indistinguishable, although larger studies are warranted to further evaluate this association.

Identifiers

PMID25653870
PMCPMC4306370

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.