ArticleKorean circulation journal2015
Effects of age on arterial stiffness and blood pressure variables in patients with newly diagnosed untreated hypertension.
Article in Korean circulation journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Vascular phenotypes in early hypertension.Journal of human hypertension · 2023Article
- Childhood environments and their relationship with sleep and ambulatory blood pressure in college students.Journal of American college health : J of ACH · 2023Article
- IGFBP-1 and IGFBP-2 are associated with a decreased pulse-wave velocity in young, healthy adults.BMC cardiovascular disorders · 2021Article
- Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension.Clinical interventions in aging · 2016Article
- Carotid Artery IMT, Blood Pressure, and Cardiovascular Risk Factors in Males and Females.International journal of exercise scienceArticle
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Authors and funding
13 authors.
Funding
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Abstract
BACKGROUND AND
objectivesTo investigate the impact of age on arterial stiffness and blood pressure (BP) variables in newly diagnosed untreated hypertension (HT). SUBJECTS AND
methodsA total of 144 patients with newly diagnosed untreated HT were divided into two groups: young group (age ≤50 years, n=71), and old group (age >50 years, n=73). BP variables were measured on office or 24 hours ambulatory BP monitoring (ABPM). Parameters of arterial stiffness were measured on pulse wave velocity (PWV). Pulse wave analysis (PWA) was compared.
resultsAlthough office BP and pulse pressure (PP) were significantly (p<0.05) higher in the young group than in the old group, BP and PP on ABPM were not significantly different. Central systolic BP and PP, augmentation pressure, augmentation index on PWA, and PWV were significantly higher or faster in the old group compared to that in the young group. Age showed significant positive correlation with both PWV and PWA variables in the young group with HT. However, age only showed significant positive correlation with PWV in the old group with HT. In the young group with HT, PWA variable showed better correlation with age than PWV.
conclusionConsidering BP levels on ABPM, office BP is prone to be overestimated in young patients with HT. Parameters of arterial stiffness measured by PWV and PWA were more affected by age rather than by BP level in patients with HT. Therefore, PWA variable might be a more sensitive marker of arterial stiffness in young patients with HT. However, PWV might be a better marker for old patients with HT.
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