Evidence map›Paper›PMID 25653532›Full record

ReviewTherapeutics and clinical risk management2015

Diagnosis and management of xerostomia and hyposalivation.

Alessandro Villa, Christopher L Connell, Silvio Abati

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Therapeutics and clinical risk management, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 178 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
178citing papers in PubMed, 8 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

178 citing papers in PubMed, 8 syntheses or guidelines pooled it, 433 citations in OpenAlex.

  1. Pooled it
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  4. Evaluating Xerostomia as a side effect of [European journal of nuclear medicine and molecular imaging · 2025
    Pooled it
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  8. Xerostomia and Aalivary Flow in Patients Taking Antihypertensive Drugs.International journal of environmental research and public health · 2020
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  13. Sodium-hyaluronate mouthwash on radiotherapy-induced xerostomia: a randomised clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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118 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Alessandro VillaDivision of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA, USA ; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA.
Christopher L ConnellDepartment of General Dentistry, Boston University Henry M Goldman School of Dental Medicine, Boston, MA, USA.
Silvio AbatiDental Clinic, Department of Health Sciences, University of Milan, Milano, Italy.
Boston University · USBrigham and Women's Hospital · USUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Xerostomia, the subjective complaint of dry mouth, and hyposalivation remain a significant burden for many individuals. Diagnosis of xerostomia and salivary gland hypofunction is dependent upon a careful and detailed history and thorough oral examination. There exist many options for treatment and symptom management: salivary stimulants, topical agents, saliva substitutes, and systemic sialogogues. The aim of this review is to investigate the current state of knowledge on management and treatment of patients affected by xerostomia and/or hyposalivation.

Indexed as

dry mouthsaliva stimulationsaliva substitutessialogogues

Identifiers

PMID25653532
PMCPMC4278738
OpenAlexW2138312572

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.