Evidence map›Paper›PMID 25653523›Full record

ArticleInternational journal of nanomedicine2015

Multifunction hexagonal liquid-crystal containing modified surface TiO2 nanoparticles and terpinen-4-ol for controlled release.

Eloísa Berbel Manaia, Renata Cristina Kiatkoski Kaminski, Anselmo Gomes de Oliveira, Marcos Antonio Corrêa, Leila Aparecida Chiavacci

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Physicochemical characterization of drug nanocarriers.International journal of nanomedicine · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eloísa Berbel ManaiaDrugs and Medicines Department, Faculty of Pharmaceutical Sciences, São Paulo State University - UNESP, Araraquara, Brazil.
Renata Cristina Kiatkoski KaminskiPhysical-Chemistry Department, Chemistry Institute, São Paulo State University - UNESP, Araraquara, Brazil.
Anselmo Gomes de OliveiraDrugs and Medicines Department, Faculty of Pharmaceutical Sciences, São Paulo State University - UNESP, Araraquara, Brazil.
Marcos Antonio CorrêaDrugs and Medicines Department, Faculty of Pharmaceutical Sciences, São Paulo State University - UNESP, Araraquara, Brazil.
Leila Aparecida ChiavacciDrugs and Medicines Department, Faculty of Pharmaceutical Sciences, São Paulo State University - UNESP, Araraquara, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multifunctional products have been developed to combine the benefits of functional components and terpinen-4-ol (TP) delivery systems. In this way, p-toluene sulfonic acid modified titanium dioxide (TiO2) nanoparticles and TP, an antioxidant, have been incorporated in liquid-crystalline formulations for photoprotection and controlled release of the TP, respectively. By X-ray powder diffraction and diffuse reflectance spectroscopy, we noted that using p-toluene sulfonic acid as a surface modifier made it possible to obtain smaller and more transparent TiO2 nanoparticles than those commercially available. The liquid-crystalline formulation containing the inorganic ultraviolet filter was classified as broad-spectrum performance by the absorbance spectroscopy measurements. The formulations containing modified TiO2 nanoparticles and TP were determined to be in the hexagonal phase by polarized light microscopy and small-angle X-ray scattering, which makes possible the controlled released of TP following zero-order kinetics. The developed formulations can control the release of TP. Constant concentrations of the substance have been released per time unit, and the modified TiO2 nanoparticles can act as a transparent inorganic sunscreen.

Indexed as

Delayed-Action PreparationsLiquid CrystalsMicroscopy, InterferenceNanoparticlesSunscreening AgentsTerpenesTitaniumX-Ray DiffractionDelayed-Action PreparationsSunscreening AgentsTerpenesterpinenol-4Titaniumtitanium dioxidedrug deliverysol-gelsunscreentitanium dioxide

Identifiers

PMID25653523
PMCPMC4309795

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.