Evidence map›Paper›PMID 25653186›Full record

ArticleHerzschrittmachertherapie & Elektrophysiologie2015

Patients with atrial fibrillation complicated by coronary artery disease. Is a single value of sensitive cardiac troponin I on admission enough?

Dirk Bandorski, Harilaos Bogossian, Olaf Braun, Gerrit Frommeyer, Markus Zarse, Reinhard Höltgen, Christoph Liebetrau

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Article in Herzschrittmachertherapie & Elektrophysiologie, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Dirk BandorskiMedizinische Klinik 2, Universtität Giessen, Klinikstr. 33, 35392, Giessen, Germany, dirk.bandorski@hkw.med.uni-giessen.de.
Harilaos Bogossian
Olaf Braun
Gerrit Frommeyer
Markus Zarse
Reinhard Höltgen
Christoph Liebetrau
Klinikum Lüdenscheid · DEUniversity of Giessen · DEPraxis für Humangenetik · DESt. Agnes Hospital · USUniversity Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is the most common arrhythmia in the general population. Cardiac troponin I (cTnI) can be elevated in patients with AF without coexisting coronary artery disease (CAD). The aim of this study was to characterize the diagnostic accuracy and clinical usefulness of a cTnI assay for the diagnosis of CAD in patients with AF.

methodsPatients with AF undergoing coronary angiography were included in the study. The workflow chart encompassed measuring of cTnI in all patients at admission and after 6 h.

resultsPatients with CAD were older (73.8 ± 7.6 vs. 65.3 ± 12.9 years) than patients without CAD; for all other characteristics, no significant differences were observed. Of the patients, 39 had CAD [12 patients one-vessel disease (VD), 14 patients 2-VD, 13 patients 3-VD] and 16 patients had acute myocardial infarction and were undergoing percutaneous coronary intervention. There was no significant difference in cTnI concentrations between patients without and with CAD at admission (0.02 vs. 0.03 ng/ml, respectively); however, a difference was noted after 6 h (0.03 vs. 0.06 ng/ml, respectively).

conclusionAF patients both without and with CAD showed similar cTnI concentrations at admission. A second validation of cTnI is mandatory for all patients.

Indexed as

AgedAtrial FibrillationBiomarkersComorbidityCoronary Artery DiseaseFemaleGermanyHumansIncidenceMalePatient AdmissionReproducibility of ResultsRisk AssessmentSensitivity and SpecificityTroponin IBiomarkersTroponin I

Identifiers

PMID25653186
OpenAlexW1273536953

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.