ArticleParasitology research2015
Mosquitocidal and antibacterial activity of green-synthesized silver nanoparticles from Aloe vera extracts: towards an effective tool against the malaria vector Anopheles stephensi?
Article in Parasitology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.
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Who cites it
54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 226 citations in OpenAlex.
- Nanopesticides: A Systematic Review of Their Prospects With Special Reference to Tea Pest Management.Frontiers in nutrition · 2021Pooled it
- Plant-borne ovicides in the fight against mosquito vectors of medical and veterinary importance: a systematic review.Parasitology research · 2015Pooled it
- Evaluation of the Larvicidal and Repellency of Extracts and Silver Nanoparticles Biosynthesized withJournal of arthropod-borne diseases · 2025Article
- Review
- Tiny Green Army: Fighting Malaria with Plants and Nanotechnology.Pharmaceutics · 2024Review
- Bio-Fabricated Silver Nanoparticles from the Leaf Extract of the Poisonous Plant,Pharmaceutics · 2023Article
- Metallic and non-metallic nanoparticles from plant, animal, and fisheries wastes: potential and valorization for application in agriculture.Environmental science and pollution research international · 2022Review
- Sustainable development through the bio-fabrication of ecofriendly ZnO nanoparticles and its approaches to toxicology and environmental protection.Biomass conversion and biorefinery · 2022Article
- Green Synthesis of Selenium Nanoparticles Mediated by Nilgirianthus ciliates Leaf Extracts for Antimicrobial Activity on Foodborne Pathogenic Microbes and Pesticidal Activity Against Aedes aegypti with Molecular Docking.Biological trace element research · 2022Article
- Mycosynthesis, Characterization, and Mosquitocidal Activity of Silver Nanoparticles Fabricated byJournal of fungi (Basel, Switzerland) · 2022Article
- Efficacy and side effects of bio-fabricated sardine fish scale silver nanoparticles against malarial vector Anopheles stephensi.Scientific reports · 2021Article
- Mechanistic aspects of plant-based silver nanoparticles against multi-drug resistant bacteria.Heliyon · 2021Review
- Zinc oxide nanoparticles using plant Lawsonia inermis and their mosquitocidal, antimicrobial, anticancer applications showing moderate side effects.Scientific reports · 2021Article
- Curcumin-Chitosan Nanocomposite Formulation ContainingBioMed research international · 2021Article
- Role of Biosynthesized Ag-NPs UsingFrontiers in pharmacology · 2021Article
- Antiamoebic activity of plant-based natural products and their conjugated silver nanoparticles against Acanthamoeba castellanii (ATCC 50492).AMB Express · 2020Article
- Lichen Parmelia sulcata mediated synthesis of gold nanoparticles: an eco-friendly tool against Anopheles stephensi and Aedes aegypti.Environmental science and pollution research international · 2019Article
- Antibacterial Effect of Silver Nanoparticles Synthesized UsingBioinorganic chemistry and applications · 2019Article
- The potential effects of silver and gold nanoparticles as molluscicides and cercaricides on Schistosoma mansoni.Parasitology research · 2018Article
- New insights on the green synthesis of metallic nanoparticles using plant and waste biomaterials: current knowledge, their agricultural and environmental applications.Environmental science and pollution research international · 2018Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mosquitoes represent an important threat for lives of millions of people worldwide, acting as vectors for devastating pathogens, such as malaria, yellow fever, dengue, and West Nile. In addition, pathogens and parasites polluting water also constitute a severe plague for populations of developing countries. Here, we investigated the mosquitocidal and antibacterial properties of Aloe vera leaf extract and silver nanoparticles synthesized using A. vera extract. Mosquitocidal properties were assessed in laboratory against larvae (I-IV instar) and pupae of the malaria vector Anopheles stephensi. Green-synthesized silver nanoparticles were tested against An. stephensi also in field conditions. Antibacterial properties of nanoparticles were evaluated against Bacillus subtilis, Klebsiella pneumoniae, and Salmonella typhi using the agar disk diffusion and minimum inhibitory concentration protocol. The synthesized silver nanoparticles were characterized by UV-vis spectrum, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and X-ray diffraction (XRD). In laboratory conditions, the A. vera extract was toxic against An. stephensi larvae and pupae, even at low dosages. LC50 were 48.79 ppm (I instar), 59.09 ppm (II instar), 70.88 ppm (III instar), 83.58 ppm (IV instar), and 152.55 ppm (pupae). Green-synthesized silver nanoparticles were highly toxic against An. stephensi. LC50 were 3.825 ppm (I instar), 4.119 ppm (II instar), 4.982 ppm (III instar), 5.711 ppm (IV instar), and 6.113 ppm (pupae). In field conditions, the application of A. vera-synthesized silver nanoparticles (10 × LC50) leads to An. stephensi larval reduction of 74.5, 86.6, and 97.7%, after 24, 48, and 72 h, respectively. Nanoparticles also showed antibacterial properties, and the maximum concentration tested (150 mg/L) evoked an inhibition zone wider than 80 mm in all tested bacterium species. This study adds knowledge about the use of green synthesis of nanoparticles in medical entomology and parasitology, allowing us to propose A. vera-synthesized silver nanoparticles as effective candidates to develop newer and safer mosquitocidal control tools.
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