ArticleJournal of evolutionary biology2015
Can paternal leakage maintain sexually antagonistic polymorphism in the cytoplasm?
Article in Journal of evolutionary biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Support for Y-compensation of mother's curse affecting lifespan in Drosophila melanogaster.Heredity · 2024Article
- Mother's Curse effects on lifespan and aging.Frontiers in aging · 2024Review
- Sexual antagonism in sequential hermaphrodites.Proceedings. Biological sciences · 2023Article
- Review
- Sex-biased demography modulates male harm across the genome.Proceedings. Biological sciences · 2021Article
- Selection for biparental inheritance of mitochondria under hybridization and mitonuclear fitness interactions.Proceedings. Biological sciences · 2021Article
- The Reserve/Maximum Capacity of Melatonin's Synthetic Function for the Potential Dimorphism of Melatonin Production and Its Biological Significance in Mammals.Molecules (Basel, Switzerland) · 2021Review
- mtDNA Heteroplasmy: Origin, Detection, Significance, and Evolutionary Consequences.Life (Basel, Switzerland) · 2021Review
- Hybridization, sex-specific genomic architecture and local adaptation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Review
- Coadaptation of mitochondrial and nuclear genes, and the cost of mother's curse.Proceedings. Biological sciences · 2018Article
- Article
- Sexual conflict explains the extraordinary diversity of mechanisms regulating mitochondrial inheritance.BMC biology · 2017Article
- Mitonuclear Ecology.Molecular biology and evolution · 2015Review
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
A growing number of studies in multicellular organisms highlight low or moderate frequencies of paternal transmission of cytoplasmic organelles, including both mitochondria and chloroplasts. It is well established that strict maternal inheritance is selectively blind to cytoplasmic elements that are deleterious to males - 'mother's curse'. But it is not known how sensitive this conclusion is to slight levels of paternal cytoplasmic leakage. We assess the scope for polymorphism when individuals bear multiple cytoplasmic alleles in the presence of paternal leakage, bottlenecks and recurrent mutation. When fitness interactions among cytoplasmic elements within an individual are additive, we find that sexually antagonistic polymorphism is restricted to cases of strong selection on males. However, when fitness interactions among cytoplasmic elements are nonlinear, much more extensive polymorphism can be supported in the cytoplasm. In particular, mitochondrial mutants that have strong beneficial fitness effects in males and weak deleterious fitness effects in females when rare (i.e. 'reverse dominance') are strongly favoured under paternal leakage. We discuss how such epistasis could arise through preferential segregation of mitochondria in sex-specific somatic tissues. Our analysis shows how paternal leakage can dampen the evolution of deleterious male effects associated with predominant maternal inheritance of cytoplasm, potentially explaining why 'mother's curse' is less pervasive than predicted by earlier work.
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