ArticleJournal of the American Society for Mass Spectrometry2015
Complete hexose isomer identification with mass spectrometry.
Article in Journal of the American Society for Mass Spectrometry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed.
- Chiral Carbohydrate Adducts are Effective for Enantiomeric Ion Mobility Separations.Journal of the American Society for Mass Spectrometry · 2026Article
- Urinary biochemical ecology reveals microbiome-metabolite interactions and metabolic markers of recurrent urinary tract infection.NPJ biofilms and microbiomes · 2025Article
- Analytical Strategies for Natural Mono- and Disaccharide Isomer Differentiation: Techniques and Applications.Drug design, development and therapy · 2025Review
- Long-Term Creatine Supplementation Improves Cognitive and Hippocampal Structural Plasticity Impairments in a D-Gal-Induced Aging Model via Increasing CK-BB Activity in the Brain.Food science & nutrition · 2025Article
- Integration of Artificial Intelligence and Quantum Transport toward Stereoselective Identification of Carbohydrate Isomers.ACS central science · 2024Article
- Distinguishing Oligosaccharide Isomers Using Far-Infrared Ion Spectroscopy: Identification of Biomarkers for Inborn Errors of Metabolism.Analytical chemistry · 2023Article
- Statistical Framework for Identifying Differences in Similar Mass Spectra: Expanding Possibilities for Isomer Identification.Analytical chemistry · 2023Article
- The efficacy and mechanism of berberine in improving aging-related cognitive dysfunction: A study based on network pharmacology.Frontiers in neuroscience · 2023Article
- Evaluating the Utility of Temporal Compression in High-Resolution Traveling Wave-Based Cyclic Ion Mobility Separations.ACS measurement science au · 2022Article
- Effects of monosaccharide composition on quantitative analysis of total sugar content by phenol-sulfuric acid method.Frontiers in nutrition · 2022Article
- Article
- Accurate Identification of Bioactive Meliaceae Limonoids by UHPLC-MS/MS Based Structure-Fragment Relationships (SFRs).ACS omega · 2021Article
- Logically derived sequence tandem mass spectrometry for structural determination of Galactose oligosaccharides.Glycoconjugate journal · 2021Article
- Antioxidant Effects ofFrontiers in pharmacology · 2021Article
- Advancing Solutions to the Carbohydrate Sequencing Challenge.Journal of the American Chemical Society · 2019Review
- Development of a Post-Column Liquid Chromatographic Chiral Addition Method for the Separation and Resolution of Common Mammalian Monosaccharides.Journal of the American Society for Mass Spectrometry · 2019Article
- Simple Method for De Novo Structural Determination of Underivatised Glucose Oligosaccharides.Scientific reports · 2018Article
- Scope and limitations of carbohydrate hydrolysis for de novo glycan sequencing using a hydrogen peroxide/metallopeptide-based glycosidase mimetic.Carbohydrate research · 2018Article
- Simple Approach for De Novo Structural Identification of Mannose Trisaccharides.Journal of the American Society for Mass Spectrometry · 2018Article
- A High-Throughput Mass-Spectrometry-Based Assay for Identifying the Biochemical Functions of Putative Glycosidases.Chembiochem : a European journal of chemical biology · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The first analytical method is presented for the identification and absolute configuration determination of all 24 aldohexose and 2-ketohexose isomers, including the D and L enantiomers for allose, altrose, galactose, glucose, gulose, idose, mannose, talose, fructose, psicose, sorbose, and tagatose. Two unique fixed ligand kinetic method combinations were discovered to create significant enough energetic differences to achieve chiral discrimination among all 24 hexoses. Each of these 24 hexoses yields unique ratios of a specific pair of fragment ions that allows for simultaneous determination of identification and absolute configuration. This mass spectrometric-based methodology can be readily employed for accurate identification of any isolated monosaccharide from an unknown biological source. This work provides a key step towards the goal of complete de novo carbohydrate analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.