Trial reportBMC gastroenterology2015
Cap assisted colonoscopy for the detection of serrated polyps: a post-hoc analysis.
Trial report in BMC gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and Clinical Features of Sessile Serrated Polyps: A Systematic Review.Gastroenterology · 2020Pooled it
- Application of colonoscopic auxiliary devices in reducing the polyp miss rate: a prospective randomized controlled study.BMC gastroenterology · 2025Trial
- Underwater versus conventional endoscopic resection of nondiminutive nonpedunculated colorectal lesions: a prospective randomized controlled trial (with video).Gastrointestinal endoscopy · 2020Trial
- Colorectal Cancer Screening in Hereditary and Familial High-Risk Populations: Best Practices and Future Directions.International journal of cancer · 2026Review
- Mucosal imaging in colon polyps: New advances and what the future may hold.World journal of gastroenterology · 2022Review
- Standards of diagnostic colonoscopy for early-stage neoplasia: Recommendations by an Asian private group.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2019Article
- An Additional 30-s Observation of the Right-Sided Colon with Narrow Band Imaging Decreases Missed Polyps: A Pilot Study.Digestive diseases and sciences · 2018Observational
- Management of Serrated Polyps of the Colon.Current treatment options in gastroenterology · 2018Review
- Endocuff assisted colonoscopy significantly increases sessile serrated adenoma detection in veterans.Journal of gastrointestinal oncology · 2017Article
- Can Technology Improve the Quality of Colonoscopy?Current gastroenterology reports · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColonoscopy offers limited protection against right-sided colon cancer, a significant proportion of which arise from the serrated pathway of carcinogenesis. The aim of this study was to compare cap-assisted colonoscopy and standard high-definition white light colonoscopy regarding serrated polyps' detection.
methodsPost hoc analysis was performed of a previously conducted randomized controlled trial comparing standard and cap-assisted colonoscopy for adenoma detection. Randomization was stratified based on the indication of colonoscopy and all procedures were performed by three experienced endoscopists. Following cecal intubation, the colonic mucosa was carefully inspected during withdrawal of colonoscope and all polyps detected were documented for their size, location, morphology and then removed and sent for histopathology. Detection rates of significant serrated polyps between both arms were compared using the Fisher's exact test and Wilcoxon Rank Sum test.
results427 patients were enrolled (7 exclusions, 210 completed study in each arm, mean age of 61 years, 95% male, 75% Caucasian, 67% screening colonoscopies). There were no significant differences in baseline characteristics between both groups. Cap-assisted colonoscopy detected a significantly higher proportion of subjects with significant serrated polyps as well as a higher total number of significant serrated polyps compared to standard colonoscopy (12.8% vs. 6.6%, p =0.047 and 40 vs. 20,p = 0.03 respectively).
conclusionsIn this post-hoc analysis, Cap-assisted colonoscopy is a safe technique that offers a higher detection rate of significant serrated polyps when compared to standard colonoscopy. If confirmed in future trials, this simple technique has the potential to improve protection against interval colon cancers.
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