Evidence map›Paper›PMID 25652791›Full record

ArticleJournal of biomedical optics2015

Three-dimensional vibrometry of the human eardrum with stroboscopic lensless digital holography.

Morteza Khaleghi, Cosme Furlong, Mike Ravicz, Jeffrey Tao Cheng, John J Rosowski

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biomedical optics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Mammalian middle ear mechanics: A review.Frontiers in bioengineering and biotechnology · 2022
    Review
  5. Article
  6. Article
  7. Biomedical optics express · 2019
    Article
  8. Article
  9. Article
  10. In-plane and out-of-plane motions of the human tympanic membrane.The Journal of the Acoustical Society of America · 2016
    Article
  11. Article
  12. Holography applications toward medical field: An overview.The Indian journal of radiology & imaging
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Morteza KhaleghiWorcester Polytechnic Institute, Department of Mechanical Engineering, Center for Holographic Studies and Laser Micro-mechatronics, Worcester, Massachusetts 01609, United States.
Cosme FurlongWorcester Polytechnic Institute, Department of Mechanical Engineering, Center for Holographic Studies and Laser Micro-mechatronics, Worcester, Massachusetts 01609, United StatesbEaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massac.
Mike RaviczEaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, United StatescHarvard Medical School, Department of Otology and Laryngology, Boston, Massachusetts 02114, United States.
Jeffrey Tao ChengEaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, United StatescHarvard Medical School, Department of Otology and Laryngology, Boston, Massachusetts 02114, United States.
John J RosowskiEaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, United StatescHarvard Medical School, Department of Otology and Laryngology, Boston, Massachusetts 02114, United States.
Harvard University · USMassachusetts Eye and Ear Infirmary · USWorcester Polytechnic Institute · US

Funding

Computer-based Holography and Middle-Ear FunctionR01DC008642 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI ROSOWSKI, JOHN J · 2007 to 2014
$2.2M
NIDCD NIH HHS R01 DC008642
6 · The paper itself

Abstract

The eardrum or tympanic membrane (TM) transforms acoustic energy at the ear canal into mechanical motions of the ossicles. The acousto-mechanical transformer behavior of the TM is determined by its shape, three-dimensional (3-D) motion, and mechanical properties. We have developed an optoelectronic holographic system to measure the shape and 3-D sound-induced displacements of the TM. The shape of the TM is measured with dual-wavelength holographic contouring using a tunable near IR laser source with a central wavelength of 780 nm. 3-D components of sound-induced displacements of the TM are measured with the method of multiple sensitivity vectors using stroboscopic holographic interferometry. To accurately obtain sensitivity vectors, a new technique is developed and used in which the sensitivity vectors are obtained from the images of a specular sphere that is being illuminated from different directions. Shape and 3-D acoustically induced displacement components of cadaveric human TMs at several excitation frequencies are measured at more than one million points on its surface. A numerical rotation matrix is used to rotate the original Euclidean coordinate of the measuring system in order to obtain in-plane and out-of-plane motion components. Results show that in-plane components of motion are much smaller (<20%) than the out-of-plane motions’ components.

Indexed as

AcousticsAlgorithmsCadaverComputersHearingHolographyHumansImaging, Three-DimensionalInterferometryLightMembranes, ArtificialModels, TheoreticalMotionReproducibility of ResultsSoundStroboscopyMembranes, Artificial

Identifiers

PMID25652791
PMCPMC4408086
OpenAlexW2133569754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.