Evidence map›Paper›PMID 25652649›Full record

ReviewFrontiers of medicine2015

Th17 cells in autoimmune diseases.

Lei Han, Jing Yang, Xiuwen Wang, Dan Li, Ling Lv, Bin Li

Abstract readReview
PubMed Publisher
In one paragraph

Review in Frontiers of medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. T cells in health and disease.Signal transduction and targeted therapy · 2023
    Review
  6. Article
  7. Article
  8. NF-kB pathway is involved in microscopic colitis pathogenesis.The Journal of international medical research · 2022
    Article
  9. Article
  10. Smouldering fire or conflagration? An illustrated update on the concept of inflammation in pulmonary arterial hypertension.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. The Role of Gut Mucins in the Etiology of Depression.Frontiers in behavioral neuroscience · 2020
    Review
  18. Article
  19. CaBritish journal of pharmacology · 2019
    Article
  20. Metabolic regulation of TMolecular immunology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lei HanDivision of Rheumatology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Jing Yang
Xiuwen Wang
Dan Li
Ling Lv
Bin Li

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Th17 cells are a new subset of CD4(+) T cells involved in the clearance of extracellular pathogens and fungi. Accumulating evidence suggests that Th17 cells and their signature cytokines have a pivotal role in the pathogenesis of multiple autoimmune-mediated inflammatory diseases. Here, we summarize recent research progress on Th17 function in the development and pathogenesis of autoimmune diseases. We also propose to identify new small molecule compounds to manipulate Th17 function for potential therapeutic application to treat human autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren's syndrome, inflammatory bowel disease, and multiple sclerosis.

Indexed as

Autoimmune DiseasesMolecular Targeted TherapyCytokinesHumansInflammationProtein Processing, Post-TranslationalTh17 CellsCytokines

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.