Evidence map›Paper›PMID 25652324›Full record

ReviewMolecular biology reports2015

Application of molecular antiviral compounds: novel approach for durable resistance against geminiviruses.

Pranav Pankaj Sahu, Manoj Prasad

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pranav Pankaj SahuNational Institute of Plant Genome Research (NIPGR), Aruna Asaf Ali Marg, New Delhi, 110067, India.
Manoj Prasad

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both transgenic as well as traditional breeding approaches have not been completely successful in inducting resistance against geminiviruses in crop plants. This demands the utilization of non-viral, non-plant compounds possessing antiviral characteristics as an alternate and effective strategy for developing durable resistance against geminiviruses. In recent years, several antiviral molecules have been developed for the treatment of plant virus infections. These molecular antiviral compounds target various geminiviral-DNA and -protein via interacting with them or by cleaving viral RNA fragments. Applications of these proteins such as GroEL, g5g and VirE2 have also provided a convincing evidence of resistance against geminiviruses. Taking advantage of this information, we can generate robust resistance against geminiviruses in diverse crop plants. In this context, the present review provides epigrammatic information on these antiviral compounds and their mode of action in modulating virus infection.

Indexed as

Antiviral AgentsAptamers, PeptideBacterial ProteinsChaperonin 60DNA-Binding ProteinsGeminiviridaeIon ChannelsLactalbuminLactoferrinPlant DiseasesPlantsPlants, Genetically ModifiedRNA, CatalyticRNA InterferenceRNA, Small InterferingViral ProteinsAntiviral AgentsAptamers, PeptideBacterial ProteinsChaperonin 60DNA-Binding ProteinsIon ChannelsLactalbuminLactoferrinRNA, CatalyticRNA, Small InterferingViral ProteinsvirE2 protein, Agrobacterium

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.