ReviewCurrent neurology and neuroscience reports2015
Dissecting the association between migraine and stroke.
Review in Current neurology and neuroscience reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Associations of migraines with suicide ideation or attempts: A meta-analysis.Frontiers in public health · 2023Pooled it
- The Epidemiology of Migraine Headache in Arab Countries: A Systematic Review.TheScientificWorldJournal · 2020Pooled it
- A Systematic Review and Meta-Analysis of Migraine and Suicidal Ideation.The Clinical journal of pain · 2017Pooled it
- Migraine and the risk of stroke: an updated meta-analysis of prospective cohort studies.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017Pooled it
- Idiopathic Paracentral Acute Middle Maculopathy in a Healthy Pregnant Woman: A Case Report.Case reports in ophthalmological medicine · 2026Article
- Reviewing migraine-associated pathophysiology and its impact on elevated stroke risk.Frontiers in neurology · 2024Review
- The vascular Na,K-ATPase: clinical implications in stroke, migraine, and hypertension.Clinical science (London, England : 1979) · 2023Review
- Microglia Modulate Cortical Spreading Depolarizations After Ischemic Stroke: A Narrative Review.Neurocritical care · 2022Review
- Type and Severity of Migraine Determines Risk of Atrial Fibrillation in Women.Frontiers in cardiovascular medicine · 2022Article
- Risk factors and mechanisms of stroke in young adults: The FUTURE study.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2018Article
- Migraine and risk of cardiovascular diseases: Danish population based matched cohort study.BMJ (Clinical research ed.) · 2018Article
- Neurology Concepts: Young Women and Ischemic Stroke-Evaluation and Management in the Emergency Department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2018Article
- Migraine and Stroke: What's the Link? What to Do?Current neurology and neuroscience reports · 2017Review
- Headache and Its Approach in Today's NeuroIntensive Care Unit.Neurocritical care · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Migraine is a common disabling neurological disorder resulting from excessive cortical excitation and trigeminovascular afferent sensitization. In addition to aberrant neuronal processing, migraineurs are also at significant risk of vascular disease. Consequently, the impact of migraine extends well beyond the ictal headache and includes a well-documented association with acute ischemic stroke, particularly in young women with a history of migraine with aura. The association between migraine and stroke has been acknowledged for 40 years or more. However, examining the pathobiology of this association has become a more recent and critically important undertaking. The diversity of mechanisms underlying the association between migraine and stroke likely reflects the heterogenous nature of this disorder. Vasospasm, endothelial injury, platelet aggregation and prothrombotic states, cortical spreading depression, carotid dissection, genetic variants, and traditional vascular risk factors have been offered as putative mechanisms involved in migraine-related stroke risk. Assimilating these seemingly divergent pathomechanisms into a cogent understanding of migraine-related stroke will inform future studies and the development of new strategies for the prevention and treatment of migraine and stroke.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.