ArticleJournal of industrial microbiology & biotechnology2015
Organic acids from lignocellulose: Candida lignohabitans as a new microbial cell factory.
Article in Journal of industrial microbiology & biotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 38 citations in OpenAlex.
- Engineering of itaconic acid pathway via co-localization of CadA and AcnA in recombinant Escherichia coli.Biotechnology letters · 2024Article
- Current Insights in Fungal Importance-A Comprehensive Review.Microorganisms · 2023Review
- Genotypic and phenotypic diversity among Komagataella species reveals a hidden pathway for xylose utilization.Microbial cell factories · 2022Review
- Yeast GH30 Xylanase fromMolecules (Basel, Switzerland) · 2022Article
- Recent Advances in Biotechnological Itaconic Acid Production, and Application for a Sustainable Approach.Polymers · 2021Review
- Notable mixed substrate fermentation by native Kodamaea ohmeri strains isolated from Lagenaria siceraria flowers and ethanol production on paddy straw hydrolysates.Chemistry Central journal · 2018Article
- Effective approach to organic acid production from agricultural kimchi cabbage waste and its potential application.PloS one · 2018Article
- Lipid production via simultaneous conversion of glucose and xylose by a novel yeast, Cystobasidium iriomotense.PloS one · 2018Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biorefinery applications require microbial cell factories for the conversion of various sugars derived from lignocellulosic material into value-added chemicals. Here, the capabilities of the yeast Candida lignohabitans to utilize a range of such sugars is characterized. Substrates efficiently converted by this yeast include the pentoses xylose and arabinose. Genetic engineering of C. lignohabitans with the isolated endogenous GAP promoter and GAP terminator was successful. GFP expression was used as a proof of functionality for the isolated transcription elements. Expression of lactate dehydrogenase and cis-aconitate decarboxylase resulted in stable and reproducible production of lactic acid and itaconic acid, respectively. The desired organic acids were accumulated converting pure sugars as well as lignocellulosic hydrolysates. C. lignohabitans proved therefore to be a promising reliable microbial host for production of organic acids from lignocellulosic material.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.