Evidence map›Paper›PMID 2565159›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne1989

DNA sampling and informed consent.

B M Knoppers, C Laberge

Abstract read
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. From tissues to genomes.G3 (Bethesda, Md.) · 2013
    Article
  2. Review
  3. Article
  4. Bioethics for clinicians: 14. Ethics and genetics in medicine.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 1998
    Review
  5. A survey of DNA diagnostic laboratories regarding DNA banking.American journal of human genetics · 1995
    Article
  6. Code of ethics: day-to-day applications.Journal of genetic counseling · 1994
    Article
  7. Ethics of a genetic program for myotonic dystrophy.American journal of human genetics · 1991
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

B M KnoppersFaculty of Law, University of Montreal, PQ.
C Laberge

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Standard consent forms for blood and tissue sampling are inadequate for DNA sampling. However, creating new and separate forms for each type of activity associated with DNA analysis (banking, linkage analysis and genetic diagnosis) tends to dissociate the participant from what is essentially a medical continuum. Furthermore, DNA sampling involves the sharing of samples and data among centres. To ensure patient control throughout this multifaceted process, we have developed an integrated approach to obtaining consent for DNA sampling at each level of participation. Movement from one level to another is reflected in the choices offered to participants. This inclusive approach is based on the underlying principle of informed consent, namely the respect for individuality, confidentiality and freedom of choice. This approach should help practitioners of medical genetics recognize the medical context of DNA sampling.

Indexed as

Informed ConsentCanadaConfidentialityDNADNA ProbesGenetic Diseases, InbornGenetic LinkageHumansPolymorphism, Restriction Fragment LengthRiskUnited StatesDNADNA ProbesGenetics and ReproductionProfessional Patient Relationship

Identifiers

PMID2565159
PMCPMC1268974

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.